Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FTO Q9C0B1 FTO, alpha-ketoglutarate dependent dioxygenase 1.1E-07 0.519 0.828 17 64
CDKN2B-AS1 CDKN2B antisense RNA 1 0.550 0.586 16 137
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 ligase 1.00 0.630 0.414 12 11
TERT O14746 telomerase reverse transcriptase nucleic acid binding 1.00 0.393 0.828 11 7
TCF7L2 Q9NQB0 transcription factor 7 like 2 0.99 0.538 0.621 10 14
RAD51B O15315 RAD51 paralog B 2.5E-14 0.616 0.621 9 63
ESR1 P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 1.00 0.355 0.897 8 61
CASC8 cancer susceptibility 8 0.785 0.138 8 15
PDE4D Q08499 phosphodiesterase 4D 1.00 0.572 0.690 8 12
ZNF365 Q70YC4 Q70YC5 zinc finger protein 365 4.8E-04 0.685 0.448 5 14
LSP1 P33241 lymphocyte specific protein 1 1.6E-06 0.713 0.310 5 3
MYO9B Q13459 myosin IXB 1.00 0.707 0.517 5 3
RALY Q9UKM9 RALY heterogeneous nuclear ribonucleoprotein 8.4E-02 0.685 0.310 4 16
BRCA2 P51587 BRCA2, DNA repair associated nucleic acid binding 5.5E-24 0.426 0.793 4 3
CDYL2 Q8N8U2 chromodomain Y like 2 1.6E-02 1.000 0.069 4 2
BABAM1 Q9NWV8 BRISC and BRCA1 A complex member 1 0.96 0.752 0.241 3 28
ANKLE1 Q8NAG6 ankyrin repeat and LEM domain containing 1 4.3E-18 0.886 0.138 3 13
FGFR2 P21802 fibroblast growth factor receptor 2 1.00 0.398 0.759 3 12
GRID1 Q9ULK0 glutamate ionotropic receptor delta type subunit 1 1.00 0.762 0.276 3 6
DIRC3 disrupted in renal carcinoma 3 3.1E-07 0.834 0.138 3 5
TET2 Q6N021 tet methylcytosine dioxygenase 2 1.7E-40 0.499 0.586 3 4
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 1.00 0.494 0.690 3 3
TGFBR2 P37173 transforming growth factor beta receptor 2 kinase; receptor; transferase 0.15 0.437 0.793 3 3
CAPN5 O15484 calpain 5 calcium-binding protein; hydrolase; protease 2.1E-08 0.735 0.448 3 2