Source: CLINVAR

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 78 577
TTN-AS1 TTN antisense RNA 1 0.599 0.577 78 567
MIPEP Q99797 mitochondrial intermediate peptidase Enzyme 1.6E-15 0.666 0.615 51 2
LMNA P02545 lamin A/C 1.00 0.384 0.885 46 196
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692 38 249
DMD P11532 dystrophin 1.00 0.423 0.923 35 305
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808 28 131
MYBPC3 Q14896 myosin binding protein C3 8.0E-11 0.593 0.385 25 357
SLC25A42 Q86VD7 solute carrier family 25 member 42 Transporter 0.49 0.760 0.269 21 2
ABCC9 O60706 ATP binding cassette subfamily C member 9 Transporter 9.4E-09 0.552 0.692 19 17
FLNC Q14315 filamin C 1.00 0.568 0.615 18 52
TTR P02766 transthyretin Transporter 0.52 0.423 0.885 15 45
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615 11 60
TNNT2 P45379 troponin T2, cardiac type Cellular structure 2.0E-03 0.601 0.423 11 48
TPM1 P09493 tropomyosin 1 Cellular structure 1.0E-03 0.560 0.615 11 37
ACTC1 P68032 actin alpha cardiac muscle 1 Cellular structure 0.74 0.610 0.538 11 19
PKP2 Q99959 plakophilin 2 Cellular structure 3.1E-18 0.606 0.538 10 91
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885 10 60
SCN1B Q07699 sodium voltage-gated channel beta subunit 1 Ion channel 0.10 0.575 0.538 10 12
TNNI3 P19429 troponin I3, cardiac type Cellular structure 9.6E-02 0.520 0.769 9 39
CEP85L Q5SZL2 centrosomal protein 85 like 4.5E-09 0.656 0.423 9 4
PLN P26678 phospholamban 0.45 0.595 0.577 9 4
EMD P50402 emerin 0.93 0.542 0.731 8 25
CRYAB P02511 crystallin alpha B 2.2E-02 0.515 0.731 8 15