Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769 46 41
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 41 29
IRF1-AS1 Q8N8D9 IRF1 antisense RNA 1 4.2E-03 0.670 0.385 41 26
ACOXL Q9NUZ1 acyl-CoA oxidase like Enzyme 5.2E-15 0.674 0.577 40 44
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 38 29
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
THADA Q6YHU6 THADA armadillo repeat containing Receptor 4.6E-41 0.686 0.500 37 33
CUX2 O14529 cut like homeobox 2 Transcription factor 1.00 0.644 0.500 36 10
CASC15 cancer susceptibility 15 0.603 0.577 35 41
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 33 44
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 33 33
ZBTB38 Q8NAP3 zinc finger and BTB domain containing 38 Transcription factor 1.00 0.663 0.615 32 33
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 32 25
CPS1 P31327 carbamoyl-phosphate synthase 1 Enzyme 1.1E-09 0.590 0.615 32 5
CCDC26 Q8TAB7 CCDC26 long non-coding RNA 0.647 0.615 31 41
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 30 9
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885 30 6
PVT1 Pvt1 oncogene 0.495 0.731 27 31
PLCL2 Q9UPR0 phospholipase C like 2 Enzyme 1.00 0.743 0.308 27 28