Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC6A4 P31645 solute carrier family 6 member 4 transporter 0.26 0.446 0.724 26
DRD2 P14416 dopamine receptor D2 receptor 0.79 0.454 0.724 17
MAOA P21397 monoamine oxidase A nucleic acid binding; oxidoreductase; transferase 1.00 0.497 0.655 16
COMT P21964 catechol-O-methyltransferase transferase 1.3E-05 0.426 0.897 15
HTR1A P08908 5-hydroxytryptamine receptor 1A receptor 0.23 0.529 0.621 14
TPH2 Q8IWU9 tryptophan hydroxylase 2 3.3E-06 0.562 0.552 14
DRD4 P21917 dopamine receptor D4 receptor 7.1E-09 0.536 0.414 13
NPY P01303 neuropeptide Y signaling molecule 0.16 0.469 0.690 13
CLOCK O15516 clock circadian regulator 1.00 0.505 0.897 12
DRD3 P35462 dopamine receptor D3 receptor 2.0E-03 0.527 0.552 12
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 1.00 0.514 0.586 12
ACE P12821 angiotensin I converting enzyme hydrolase; protease 1.6E-37 0.367 0.897 11
CRH P06850 corticotropin releasing hormone 0.72 0.456 0.759 11
HTR2A P28223 5-hydroxytryptamine receptor 2A receptor 0.48 0.488 0.759 11
PDYN P01213 prodynorphin signaling molecule 1.3E-04 0.528 0.414 11
SAT1 P21673 spermidine/spermine N1-acetyltransferase 1 0.87 0.546 0.759 11
BDNF P23560 brain derived neurotrophic factor signaling molecule 0.70 0.382 0.828 10
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C 1.00 0.575 0.517 10
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.0E-05 0.545 0.690 10
FKBP5 Q13451 FK506 binding protein 5 calcium-binding protein; chaperone; isomerase 0.68 0.572 0.655 10
HTR2C P28335 5-hydroxytryptamine receptor 2C receptor 0.19 0.579 0.414 10
HTR3A P46098 5-hydroxytryptamine receptor 3A receptor; transporter 1.1E-10 0.639 0.310 10
LEP P41159 leptin 0.39 0.400 0.793 10
MTHFR P42898 methylenetetrahydrofolate reductase 1.2E-09 0.354 0.828 10