Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 17 14
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 10 57
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 10 32
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 7 45
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 7 15
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731 6 2
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808 5 5
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 5 5
DCLK3 Q9C098 doublecortin like kinase 3 Kinase 0.14 0.647 0.615 5 2
TNNI3K Q59H18 TNNI3 interacting kinase 3.1E-48 0.691 0.346 4 2
MAP3K15 Q6ZN16 mitogen-activated protein kinase kinase kinase 15 2.9E-32 0.792 0.231 4 1
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692 4 1
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846 3 9
TAF1 P21675 TATA-box binding protein associated factor 1 Kinase 1.00 0.581 0.808 3 5
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846 3 2
PAK5 Q9P286 p21 (RAC1) activated kinase 5 Kinase 1.00 0.631 0.462 3 2
EPHA7 Q15375 EPH receptor A7 Kinase 1.00 0.619 0.500 3 1
PKN1 Q16512 protein kinase N1 Kinase 0.20 0.647 0.692 3 1
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885 3 1
TBCK Q8TEA7 TBC1 domain containing kinase Kinase 2.1E-15 0.650 0.654 3 1
CDC42BPB Q9Y5S2 CDC42 binding protein kinase beta Kinase 1.00 0.760 0.385 3 1
CAMK2B Q13554 calcium/calmodulin dependent protein kinase II beta Kinase 0.74 0.626 0.538 2 7
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731 2 3