Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FGFR3 P22607 fibroblast growth factor receptor 3 1.8E-05 0.417 0.759 26 17
TTN Q8WZ42 titin 6.4E-84 0.534 0.655 17 29
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase 1.00 0.352 0.793 14 35
RET P07949 ret proto-oncogene 1.00 0.418 0.724 12 57
ATM Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 6.0E-46 0.401 0.862 9 44
KIT P10721 KIT proto-oncogene receptor tyrosine kinase 0.99 0.394 0.759 7 12
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 1.00 0.616 0.552 6 0
PRKDC P78527 protein kinase, DNA-activated, catalytic polypeptide kinase; nucleic acid binding; transferase 1.00 0.552 0.690 5 5
TRRAP Q9Y4A5 transformation/transcription domain associated protein kinase; nucleic acid binding; transferase 1.00 0.713 0.345 5 4
DCLK3 Q9C098 doublecortin like kinase 3 0.10 0.720 0.448 5 2
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 7.7E-04 0.534 0.690 4 3
TNNI3K Q59H18 TNNI3 interacting kinase 2.5E-47 0.743 0.172 4 2
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 1.00 0.582 0.586 4 1
MAP3K15 Q6ZN16 mitogen-activated protein kinase kinase kinase 15 1.8E-30 0.857 0.103 4 1
TAF1 P21675 TATA-box binding protein associated factor 1 kinase; nucleic acid binding; transcription factor; transferase 1.00 0.672 0.414 3 5
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 1.00 0.494 0.690 3 2
PAK3 O75914 p21 (RAC1) activated kinase 3 0.99 0.633 0.552 3 2
EPHA7 Q15375 EPH receptor A7 1.00 0.659 0.379 3 1
PKN1 Q16512 protein kinase N1 calcium-binding protein; kinase; transfer/carrier protein; transferase 0.11 0.681 0.517 3 1
PAK5 Q9P286 p21 (RAC1) activated kinase 5 0.672 0.345 3 1
TBCK Q8TEA7 TBC1 domain containing kinase enzyme modulator; hydrolase; protease 2.0E-15 0.773 0.207 3 1
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase 1.5E-69 0.493 0.759 3 0
CDC42BPB Q9Y5S2 CDC42 binding protein kinase beta kinase; transferase 1.00 0.773 0.310 3 0
TBK1 Q9UHD2 TANK binding kinase 1 kinase; transferase 0.20 0.569 0.690 2 7