Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.312 0.931 57
CCL2 P13500 C-C motif chemokine ligand 2 signaling molecule 0.62 0.353 0.897 53
BCL2 P10415 BCL2, apoptosis regulator signaling molecule 0.57 0.312 0.862 43
ACE P12821 angiotensin I converting enzyme hydrolase; protease 1.6E-37 0.367 0.897 42
NOS3 P29474 nitric oxide synthase 3 8.9E-07 0.401 0.862 41
EDN1 P05305 endothelin 1 signaling molecule 0.46 0.417 0.828 36
SERPINE1 P05121 serpin family E member 1 enzyme modulator 4.7E-02 0.384 0.793 31
CAT P04040 catalase oxidoreductase 1.9E-10 0.397 0.828 30
ICAM1 P05362 intercellular adhesion molecule 1 3.8E-02 0.386 0.897 30
BECN1 Q14457 beclin 1 enzyme modulator 0.91 0.497 0.759 27
MTOR P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 1.00 0.399 0.793 27
NOS1 P29475 nitric oxide synthase 1 1.00 0.445 0.793 25
CCL5 P13501 C-C motif chemokine ligand 5 signaling molecule 1.7E-03 0.429 0.793 24
TGFB1 P01137 transforming growth factor beta 1 signaling molecule 0.17 0.336 0.931 23
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 nucleic acid binding; receptor; transcription factor 0.98 0.427 0.793 19
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) 5.3E-10 0.431 0.897 16
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 5.0E-09 0.485 0.724 14
LIPC P11150 lipase C, hepatic type hydrolase; storage protein 2.2E-07 0.611 0.517 14
PLAU P00749 plasminogen activator, urokinase hydrolase; protease 2.1E-06 0.434 0.690 14
F2 P00734 coagulation factor II, thrombin hydrolase; protease 1.1E-03 0.466 0.793 13
RELA Q04206 RELA proto-oncogene, NF-kB subunit nucleic acid binding; transcription factor 1.00 0.456 0.828 13
ABCC3 O15438 ATP binding cassette subfamily C member 3 transporter 7.4E-27 0.542 0.690 12
EPOR P19235 erythropoietin receptor receptor 7.1E-03 0.555 0.552 12
BNIP3 Q12983 BCL2 interacting protein 3 2.1E-05 0.569 0.621 11