Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 182 355
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 119 20
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 94 70
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 93 98
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 90 362
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885 77 931
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 68 36
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 67 40
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62 3
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731 60 64
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885 58 8
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 57 2505
PAX6 P26367 paired box 6 1.00 0.450 0.769 55 109
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923 55 0
TBCD Q9BTW9 tubulin folding cofactor D Cellular structure 1.0E-07 0.599 0.615 54 20
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 51 62
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692 45 51
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846 44 0
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808 42 519
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885 42 4
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 42 0
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 41 41
LETM1 O95202 leucine zipper and EF-hand containing transmembrane protein 1 Transporter 1.2E-06 0.545 0.692 40 0