Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
---|---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 | 334 |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 | 280 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | 262 | |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | 238 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 | 234 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | 224 | |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 | 185 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | 182 | |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | 178 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 | 170 |
CAT | P04040 | catalase | Enzyme | 1.6E-10 | 0.359 | 0.962 | 169 |
IFNA2 | P01563 | interferon alpha 2 | 0.442 | 0.885 | 169 | ||
CSF3 | P09919 | colony stimulating factor 3 | 0.38 | 0.377 | 0.885 | 168 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 | 160 |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | 157 | |
INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | 153 | |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 | 148 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 | 146 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 | 145 |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 | 142 |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | 135 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | 135 | |
PLAT | P00750 | plasminogen activator, tissue type | Enzyme | 5.7E-05 | 0.445 | 0.885 | 135 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 | 133 |