Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.406 0.724 509
FGFR2 P21802 fibroblast growth factor receptor 2 1.00 0.398 0.759 422
KRAS P01116 KRAS proto-oncogene, GTPase enzyme modulator 9.0E-04 0.350 0.724 374
FLNA P21333 filamin A 1.00 0.456 0.793 373
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase 1.00 0.352 0.793 350
FGFR3 P22607 fibroblast growth factor receptor 3 1.8E-05 0.417 0.759 348
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.474 0.724 331
FGFR1 P11362 fibroblast growth factor receptor 1 1.00 0.388 0.759 329
FBN1 P35555 fibrillin 1 calcium-binding protein; cell adhesion molecule; extracellular matrix protein; signaling molecule 1.00 0.469 0.690 298
PTEN P60484 phosphatase and tensin homolog hydrolase; phosphatase 0.82 0.334 0.828 276
GJA1 P17302 gap junction protein alpha 1 cell junction protein 0.14 0.431 0.793 251
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 1.00 0.341 0.897 251
ELN P15502 elastin 2.3E-14 0.455 0.828 245
HRAS P01112 HRas proto-oncogene, GTPase enzyme modulator 8.7E-02 0.404 0.828 238
NRAS P01111 NRAS proto-oncogene, GTPase enzyme modulator 0.53 0.420 0.690 235
ZMPSTE24 O75844 zinc metallopeptidase STE24 hydrolase; protease 1.4E-15 0.527 0.690 233
PEX1 O43933 peroxisomal biogenesis factor 1 3.3E-14 0.554 0.655 231
TP63 Q9H3D4 tumor protein p63 transcription factor 1.00 0.419 0.759 227
EP300 Q09472 E1A binding protein p300 nucleic acid binding; transcription factor; transferase 1.00 0.489 0.828 215
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 8.1E-22 0.507 0.690 211
PEX5 P50542 peroxisomal biogenesis factor 5 membrane traffic protein; receptor 1.1E-04 0.555 0.690 206
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.466 0.690 206
MED12 Q93074 mediator complex subunit 12 nucleic acid binding; transcription factor 1.00 0.528 0.655 205
POLG P54098 DNA polymerase gamma, catalytic subunit nucleic acid binding; transferase 1.3E-09 0.477 0.724 205