Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BCHE P06276 butyrylcholinesterase 1.1E-12 0.503 0.793 35 27
FGFR3 P22607 fibroblast growth factor receptor 3 1.8E-05 0.417 0.759 26 17
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 0.71 0.443 0.793 18 13
TTN Q8WZ42 titin 6.4E-84 0.534 0.655 17 29
STK11 Q15831 serine/threonine kinase 11 0.99 0.467 0.655 17 15
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 transporter 0.88 0.527 0.552 16 343
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.474 0.724 16 27
ATP6 P00846 ATP synthase F0 subunit 6 0.596 0.483 16 6
POLG P54098 DNA polymerase gamma, catalytic subunit nucleic acid binding; transferase 1.3E-09 0.477 0.724 15 40
FGFR2 P21802 fibroblast growth factor receptor 2 1.00 0.398 0.759 15 36
PTEN P60484 phosphatase and tensin homolog hydrolase; phosphatase 0.82 0.334 0.828 15 29
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 1.00 0.341 0.897 15 23
NRAS P01111 NRAS proto-oncogene, GTPase enzyme modulator 0.53 0.420 0.690 15 9
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 1.8E-03 0.352 0.862 15 4
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase 1.00 0.352 0.793 14 35
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.38 0.321 0.828 14 30
APC P25054 APC, WNT signaling pathway regulator 1.00 0.397 0.828 13 11
APOE P02649 apolipoprotein E 1.7E-03 0.352 0.931 13 11
LMNA P02545 lamin A/C 1.00 0.406 0.724 12 107
RET P07949 ret proto-oncogene 1.00 0.418 0.724 12 57
TP63 Q9H3D4 tumor protein p63 transcription factor 1.00 0.419 0.759 12 17
MTOR P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 1.00 0.399 0.793 12 9
COL7A1 Q02388 collagen type VII alpha 1 chain receptor 8.9E-42 0.552 0.586 11 37
FLNA P21333 filamin A 1.00 0.456 0.793 11 22