Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.505 0.769 5.5E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1990 1990
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
serpin family A member 1 0.410 0.923 6.8E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1991 1991
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
platelet derived growth factor subunit B 0.488 0.846 0.77
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 1993 2011
Entrez Id: 5154
Gene Symbol: PDGFA
PDGFA
platelet derived growth factor subunit A 0.533 0.731 0.81
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1993 1993
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 1 0 1994 2010
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 3 0 1996 2019
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
arachidonate 5-lipoxygenase activating protein 0.612 0.731 7.1E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1996 1996
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 2 0 1998 2018
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
prostaglandin I2 synthase 0.617 0.654 1.2E-09
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 1999 2004
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
solute carrier family 6 member 4 0.429 0.808 0.25
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 3 0 2001 2009
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
phosphodiesterase 3A 0.670 0.577 1.9E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2002 2008
Entrez Id: 11318
Gene Symbol: GPR182
GPR182
G protein-coupled receptor 182 0.691 0.462 1.4E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
tachykinin precursor 1 0.424 0.923 0.75
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 6865
Gene Symbol: TACR2
TACR2
tachykinin receptor 2 0.700 0.500 8.8E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 10800
Gene Symbol: CYSLTR1
CYSLTR1
cysteinyl leukotriene receptor 1 0.593 0.769 1.2E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.493 0.769 9.7E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.510 None 1.000 1 0 2003 2016
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
tachykinin receptor 1 0.502 0.885 3.8E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
endothelin receptor type B 0.470 0.846 9.2E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 2 0 2004 2008
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2004 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2004 2009
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
endothelin receptor type A 0.426 0.885 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2004 2010
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2004 2015
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2011