Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
SMAD family member 9 0.666 0.308 6.4E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 11318
Gene Symbol: GPR182
GPR182
G protein-coupled receptor 182 0.691 0.462 1.4E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 211
Gene Symbol: ALAS1
ALAS1
5'-aminolevulinate synthase 1 0.705 0.462 0.11
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
potassium voltage-gated channel subfamily A member 5 0.606 0.500 1.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2010 2017
Entrez Id: 6865
Gene Symbol: TACR2
TACR2
tachykinin receptor 2 0.700 0.500 8.8E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 522
Gene Symbol: ATP5PF
ATP5PF
ATP synthase peripheral stalk subunit F6 0.716 0.538 6.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2016 2016
Entrez Id: 64344
Gene Symbol: HIF3A
HIF3A
hypoxia inducible factor 3 subunit alpha 0.682 0.538 1.5E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 3036
Gene Symbol: HAS1
HAS1
hyaluronan synthase 1 0.670 0.577 1.3E-12
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 3373
Gene Symbol: HYAL1
HYAL1
hyaluronidase 1 0.633 0.577 1.9E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
phosphodiesterase 3A 0.670 0.577 1.9E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 55669
Gene Symbol: MFN1
MFN1
mitofusin 1 0.644 0.577 2.5E-10
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 8692
Gene Symbol: HYAL2
HYAL2
hyaluronidase 2 0.644 0.577 0.19
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 55512
Gene Symbol: SMPD3
SMPD3
sphingomyelin phosphodiesterase 3 0.659 0.615 0.59
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2009 2009
Entrez Id: 284119
Gene Symbol: CAVIN1
CAVIN1
caveolae associated protein 1 0.559 0.654 5.0E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2012 2013
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
prostaglandin I2 synthase 0.617 0.654 1.2E-09
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 1999 2004
Entrez Id: 10266
Gene Symbol: RAMP2
RAMP2
receptor activity modifying protein 2 0.626 0.654 5.1E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 2053
Gene Symbol: EPHX2
EPHX2
epoxide hydrolase 2 0.568 0.654 1.8E-21
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2009 2009
Entrez Id: 3037
Gene Symbol: HAS2
HAS2
hyaluronan synthase 2 0.588 0.692 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 3038
Gene Symbol: HAS3
HAS3
hyaluronan synthase 3 0.644 0.692 0.88
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 3397
Gene Symbol: ID1
ID1
inhibitor of DNA binding 1, HLH protein 0.544 0.692 3.1E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
SMAD family member 1 0.533 0.731 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2007 2008
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
collagen type IV alpha 1 chain 0.484 0.731 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2015 2015
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
endothelial PAS domain protein 1 0.454 0.731 0.60
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
arachidonate 5-lipoxygenase activating protein 0.612 0.731 7.1E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1996 1996