Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.493 0.769 9.7E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.510 None 1.000 1 0 2003 2016
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2011
Entrez Id: 211
Gene Symbol: ALAS1
ALAS1
5'-aminolevulinate synthase 1 0.705 0.462 0.11
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 3 0 1996 2019
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
arachidonate 5-lipoxygenase activating protein 0.612 0.731 7.1E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1996 1996
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
angiopoietin 1 0.446 0.808 0.95
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2006 2008
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
angiopoietin 2 0.410 0.846 0.83
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2009 2009
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 0.529 0.808 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
ATP synthase F1 subunit alpha 0.604 0.731 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2011 2011
Entrez Id: 522
Gene Symbol: ATP5PF
ATP5PF
ATP synthase peripheral stalk subunit F6 0.716 0.538 6.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2016 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2008 2008
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
BCL2 like 1 0.493 0.885 0.94
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
bradykinin receptor B2 0.585 0.808 0.12
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
baculoviral IAP repeat containing 5 0.495 0.731 5.6E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 846
Gene Symbol: CASR
CASR
calcium sensing receptor 0.410 0.846 4.7E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2004 2013
Entrez Id: 284119
Gene Symbol: CAVIN1
CAVIN1
caveolae associated protein 1 0.559 0.654 5.0E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2012 2013
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 2 0 1998 2018
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2005 2009
Entrez Id: 958
Gene Symbol: CD40
CD40
CD40 molecule 0.396 0.846 0.85
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2015 2015
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2004 2015
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
cyclin dependent kinase inhibitor 1A 0.403 0.769 1.9E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2014 2014
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
cyclin dependent kinase inhibitor 1B 0.409 0.769 0.62
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 1191
Gene Symbol: CLU
CLU
clusterin 0.426 0.885 7.8E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2015 2015
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
collagen type I alpha 1 chain 0.430 0.808 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2015 2015