Source: CTD_human

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.995 9 0 1997 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.500 None 0.948 7 0 1992 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.979 6 0 1993 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.500 None 0.981 6 0 1991 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.958 4 0 2001 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.960 4 0 1984 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.946 3 0 1996 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.500 None 0.966 3 0 1991 2020
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.370 None 0.889 3 0 2004 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.600 None 1.000 3 0 1997 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 3 0 1993 2020
Entrez Id: 28234
Gene Symbol: SLCO1B3
SLCO1B3
solute carrier organic anion transporter family member 1B3 0.592 0.769 5.3E-24
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.310 None 1.000 2 0 2008 2014
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 0.666 0.577 4.3E-14
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.310 None 1.000 2 0 2004 2017
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
baculoviral IAP repeat containing 5 0.495 0.731 5.6E-02
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.300 None 1.000 2 0 2005 2009
Entrez Id: 3725
Gene Symbol: JUN
JUN
Jun proto-oncogene, AP-1 transcription factor subunit 0.442 0.885 6.0E-02
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.350 None 1.000 2 0 2003 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 0.979 2 0 1989 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.350 None 0.833 2 0 1993 2015
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.400 None 1.000 2 0 1994 2020
Entrez Id: 2348
Gene Symbol: FOLR1
FOLR1
folate receptor alpha 0.522 0.885 0.13
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.310 None 1.000 2 0 2005 2018
Entrez Id: 54739
Gene Symbol: XAF1
XAF1
XIAP associated factor 1 0.587 0.769 6.8E-12
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.350 None 1.000 2 0 2005 2010
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
proliferating cell nuclear antigen 0.382 0.846 0.98
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.350 None 1.000 2 0 1998 2014
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.340 None 1.000 2 0 2005 2012
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
nuclear factor kappa B subunit 1 0.396 0.923 1.00
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.330 None 1.000 2 0 2009 2013
Entrez Id: 160728
Gene Symbol: SLC5A8
SLC5A8
solute carrier family 5 member 8 0.615 0.577 5.0E-16
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.380 None 1.000 2 0 2003 2017
Entrez Id: 553158
Gene Symbol: PRR5-ARHGAP8
PRR5-ARHGAP8
PRR5-ARHGAP8 readthrough 0.821 0.154 2.1E-28
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
disease 0.300 None 1.000 1 0 2014 2014