| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.906 | 1 | 0 | 1997 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.390 | None | 1.000 | 1 | 0 | 2001 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.950 | 1 | 0 | 1994 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.400 | None | 0.900 | 1 | 0 | 1997 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.900 | limited | 0.865 | 4 | 0 | 2001 | 2019 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2004 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.370 | None | 1.000 | 1 | 0 | 2011 | 2019 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.500 | None | 0.923 | 1 | 0 | 1996 | 2017 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.500 | None | 0.859 | 3 | 0 | 1997 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.600 | None | 0.780 | 1 | 0 | 1995 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.530 | None | 1.000 | 1 | 0 | 2011 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.400 | None | 0.932 | 4 | 0 | 1998 | 2020 | ||||||||
|
fibroblast growth factor receptor 1 | 0.362 | 0.885 | 1.00 |
|
disease | 0.420 | None | 1.000 | 1 | 0 | 2006 | 2017 | ||||||||
|
kinase insert domain receptor | 0.378 | 0.885 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2016 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.350 | None | 1.000 | 1 | 0 | 2005 | 2018 | ||||||||
|
interleukin 2 receptor subunit alpha | 0.389 | 0.885 | 5.5E-02 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 1994 | 2019 | ||||||||
|
nuclear receptor subfamily 3 group C member 1 | 0.393 | 0.885 | 0.97 |
|
disease | 0.400 | None | 0.929 | 2 | 0 | 2000 | 2019 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
disease | 0.500 | None | 0.887 | 4 | 0 | 1984 | 2020 | ||||||||
|
thrombospondin 1 | 0.407 | 0.885 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2012 | ||||||||
|
nitric oxide synthase 1 | 0.408 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.964 | 1 | 0 | 1995 | 2019 | ||||||||
|
haptoglobin | 0.412 | 0.885 | 1.7E-05 |
|
disease | 0.350 | None | 1.000 | 1 | 0 | 1985 | 2020 | ||||||||
|
coagulation factor II, thrombin | 0.415 | 0.885 | 1.1E-03 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2015 | 2017 | ||||||||
|
chitinase 3 like 1 | 0.419 | 0.885 | 1.1E-05 |
|
disease | 0.500 | None | 0.900 | 0 | 0 | 2003 | 2019 | ||||||||
|
neurotrophic receptor tyrosine kinase 1 | 0.422 | 0.808 | 2.0E-06 |
|
disease | 0.360 | None | 1.000 | 1 | 0 | 1998 | 2019 | ||||||||
|
tachykinin precursor 1 | 0.424 | 0.923 | 0.75 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2005 | 2005 |