Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1495
Gene Symbol: CTNNA1
CTNNA1
catenin alpha 1 0.636 0.483 0.98
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 0 0
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
Hereditary Nonpolyposis Colorectal Cancer
disease 1.000 definitive 0.950 9 0 1992 2018
Entrez Id: 5378
Gene Symbol: PMS1
PMS1
PMS1 homolog 1, mismatch repair system component 0.600 0.552 1.5E-16
Hereditary Nonpolyposis Colorectal Cancer
disease 0.400 1.000 4 0 1994 2005
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
epoxide hydrolase 1 0.510 0.759 3.7E-09
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 3 0 1994 2015
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
mutS homolog 3 0.507 0.621 8.1E-31
Hereditary Nonpolyposis Colorectal Cancer
disease 0.340 limited 0.750 6 0 1996 2017
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
cyclin dependent kinase inhibitor 1B 0.424 0.724 0.66
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 8 0 1998 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.432 0.759 0.11
Hereditary Nonpolyposis Colorectal Cancer
disease 0.310 limited 1.000 6 0 1998 2016
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
exonuclease 1 0.672 0.448 8.7E-13
Hereditary Nonpolyposis Colorectal Cancer
disease 0.340 disputed 1.000 6 0 2000 2017
Entrez Id: 580
Gene Symbol: BARD1
BARD1
BRCA1 associated RING domain 1 0.624 0.379 2.2E-24
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 4 0 2001 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
checkpoint kinase 2 0.494 0.621 1.2E-23
Hereditary Nonpolyposis Colorectal Cancer
disease 0.320 limited 1.000 12 0 2003 2017
Entrez Id: 79695
Gene Symbol: GALNT12
GALNT12
polypeptide N-acetylgalactosaminyltransferase 12 0.752 0.241 6.6E-06
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 2 0 2004 2009
Entrez Id: 472
Gene Symbol: ATM
ATM
ATM serine/threonine kinase 0.401 0.862 6.0E-46
Hereditary Nonpolyposis Colorectal Cancer
disease 0.310 moderate 1.000 6 0 2006 2017
Entrez Id: 22909
Gene Symbol: FAN1
FAN1
FANCD2 and FANCI associated nuclease 1 0.659 0.414 1.9E-25
Hereditary Nonpolyposis Colorectal Cancer
disease 0.500 limited 4 0 2010 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
partner and localizer of BRCA2 0.569 0.552 7.3E-20
Hereditary Nonpolyposis Colorectal Cancer
disease 0.310 limited 1.000 7 0 2013 2018
Entrez Id: 6224
Gene Symbol: RPS20
RPS20
ribosomal protein S20 0.773 0.172 2.4E-02
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 2 0 2014 2017
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.503 0.759 1.00
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 2 0 2015 2016
Entrez Id: 64218
Gene Symbol: SEMA4A
SEMA4A
semaphorin 4A 0.616 0.517 1.8E-05
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 2 0 2015 2017
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
X-ray repair cross complementing 4 0.550 0.724 8.1E-07
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 1 0 2015 2015
Entrez Id: 64332
Gene Symbol: NFKBIZ
NFKBIZ
NFKB inhibitor zeta 0.735 0.310 1.00
Hereditary Nonpolyposis Colorectal Cancer
disease 0.300 limited 1 0 2015 2015