Source: CTD_human

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.980 2 0 1990 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.936 1 0 1991 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.978 1 0 1992 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.976 3 0 1994 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.982 4 0 1994 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.976 1 0 2003 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.973 3 0 1988 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.962 1 0 1996 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.991 5 0 1996 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.976 1 0 1997 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.968 2 0 1998 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 1 0 1997 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.996 2 0 2001 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.952 1 0 1991 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 1 0 2009 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.962 1 0 1992 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.350 None 1.000 1 0 2007 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.970 1 0 1989 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.991 1 0 2003 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.983 6 0 1993 2020
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 1 0 1993 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.350 None 1.000 1 0 2004 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.959 1 0 1990 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.971 1 0 1991 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.989 1 0 1996 2020