| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
histamine receptor H2 | 0.647 | 0.462 | 0.12 |
|
phenotype | 0.300 | None | 1.000 | 1 | 0 | 1983 | 1983 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
phenotype | 0.400 | None | 0.973 | 3 | 0 | 1988 | 2020 | ||||||||
|
epidermal growth factor | 0.357 | 0.923 | 8.5E-17 |
|
phenotype | 0.400 | None | 0.990 | 2 | 0 | 1989 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
phenotype | 0.600 | None | 0.970 | 1 | 0 | 1989 | 2020 | ||||||||
|
NME/NM23 nucleoside diphosphate kinase 1 | 0.443 | 0.808 | 3.2E-03 |
|
phenotype | 0.400 | None | 0.940 | 1 | 0 | 1989 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.400 | None | 0.980 | 2 | 0 | 1990 | 2020 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
phenotype | 0.400 | None | 0.959 | 1 | 0 | 1990 | 2019 | ||||||||
|
CD44 molecule (Indian blood group) | 0.363 | 0.962 | 2.4E-07 |
|
phenotype | 0.400 | None | 0.979 | 1 | 0 | 1990 | 2020 | ||||||||
|
plasminogen activator, urokinase | 0.425 | 0.923 | 2.3E-06 |
|
phenotype | 0.400 | None | 0.981 | 1 | 0 | 1990 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
phenotype | 0.400 | None | 0.952 | 1 | 0 | 1991 | 2020 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
phenotype | 0.400 | None | 0.971 | 1 | 0 | 1991 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
phenotype | 0.600 | None | 0.936 | 1 | 0 | 1991 | 2020 | ||||||||
|
S100 calcium binding protein A4 | 0.448 | 0.769 | 6.2E-03 |
|
phenotype | 0.400 | None | 0.962 | 2 | 0 | 1992 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
phenotype | 0.400 | None | 0.962 | 1 | 0 | 1992 | 2020 | ||||||||
|
colony stimulating factor 1 receptor | 0.448 | 0.808 | 0.13 |
|
phenotype | 0.400 | None | 1.000 | 1 | 0 | 1992 | 2018 | ||||||||
|
galectin 3 | 0.392 | 0.846 | 2.3E-05 |
|
phenotype | 0.400 | None | 0.986 | 1 | 0 | 1992 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
phenotype | 0.400 | None | 0.978 | 1 | 0 | 1992 | 2020 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
phenotype | 0.600 | None | 0.983 | 6 | 0 | 1993 | 2020 | ||||||||
|
matrix metallopeptidase 1 | 0.385 | 0.885 | 7.7E-18 |
|
phenotype | 0.400 | None | 0.989 | 4 | 0 | 1993 | 2020 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
phenotype | 0.400 | None | 0.960 | 2 | 0 | 1993 | 2020 | ||||||||
|
hepatocyte growth factor | 0.374 | 0.885 | 1.00 |
|
phenotype | 0.400 | None | 0.986 | 1 | 0 | 1993 | 2019 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
phenotype | 0.400 | None | 1.000 | 1 | 0 | 1993 | 2019 | ||||||||
|
oncostatin M | 0.505 | 0.769 | 0.59 |
|
phenotype | 0.400 | None | 1.000 | 1 | 0 | 1993 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
phenotype | 0.400 | None | 0.982 | 4 | 0 | 1994 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
phenotype | 0.400 | None | 0.976 | 3 | 0 | 1994 | 2020 |