Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.600 None 1.000 1 0 1998 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.600 None 0.964 1 0 2008 2020
Entrez Id: 1593
Gene Symbol: CYP27A1
CYP27A1
cytochrome P450 family 27 subfamily A member 1 0.538 0.731 5.3E-19
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.450 None 1.000 1 0 2000 2013
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.400 None 0.950 1 0 2003 2019
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
phospholipase A2 group IIA 0.488 0.808 9.7E-02
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.400 None 1.000 1 0 1999 2018
Entrez Id: 337
Gene Symbol: APOA4
APOA4
apolipoprotein A4 0.582 0.577 5.5E-06
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.400 None 1.000 1 0 1994 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.400 None 0.933 1 0 2002 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
lipoprotein(a) 0.444 0.769 6.6E-89
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.400 None 0.957 1 0 1987 2020
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
plasminogen activator, tissue type 0.445 0.885 5.7E-05
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.360 None 1.000 1 0 1995 2010
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
insulin like growth factor 2 0.390 0.885 4.4E-02
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.330 None 1.000 1 0 2002 2013
Entrez Id: 356
Gene Symbol: FASLG
FASLG
Fas ligand 0.430 0.885 0.18
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.310 None 1.000 1 0 2004 2004
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.300 None 0.923 1 0 1992 2020
Entrez Id: 958
Gene Symbol: CD40
CD40
CD40 molecule 0.396 0.846 0.85
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.300 None 0.963 1 0 1997 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.260 None 1.000 1 0 2008 2019
Entrez Id: 2147
Gene Symbol: F2
F2
coagulation factor II, thrombin 0.415 0.885 1.1E-03
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.260 None 1.000 1 0 2002 2019
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
heat shock protein family D (Hsp60) member 1 0.432 0.808 0.99
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 0.963 1 0 1996 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 0.958 1 0 1993 2020
Entrez Id: 6401
Gene Symbol: SELE
SELE
selectin E 0.447 0.808 7.9E-10
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 1.000 1 0 1994 2019
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
proprotein convertase subtilisin/kexin type 9 0.482 0.808 2.7E-17
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 0.992 1 0 2006 2020
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 1.000 1 0 1994 2019
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 0.923 1 0 2005 2019
Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
C-X3-C motif chemokine ligand 1 0.478 0.808 0.61
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 0.909 1 0 2004 2019
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
matrix metallopeptidase 12 0.484 0.885
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 1.000 1 0 2000 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 1.000 1 0 2005 2019
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
platelet and endothelial cell adhesion molecule 1 0.426 0.846
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
disease 0.100 None 1.000 1 0 2002 2017