Source: CTD_human

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.600 None 1.000 11 0 1998 2015
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 8 0 2002 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.989 8 0 1991 2018
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.900 None 0.982 7 0 1990 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 6 0 1999 2019
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
dihydropyrimidine dehydrogenase 0.493 0.846 3.4E-22
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.600 None 0.952 5 0 1999 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.978 4 0 2002 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.985 4 0 1997 2019
Entrez Id: 10297
Gene Symbol: APC2
APC2
APC regulator of WNT signaling pathway 2 0.582 0.654 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 3 0 2008 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.983 3 0 1990 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 3 0 1997 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.401 0.808 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 1.000 3 0 1996 2016
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
secreted frizzled related protein 1 0.479 0.846 0.96
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.330 None 1.000 2 0 2006 2009
Entrez Id: 59352
Gene Symbol: LGR6
LGR6
leucine rich repeat containing G protein-coupled receptor 6 0.502 0.923 2.9E-06
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 2 0 2008 2011
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.310 None 1.000 2 0 2008 2018
Entrez Id: 23345
Gene Symbol: SYNE1
SYNE1
spectrin repeat containing nuclear envelope protein 1 0.511 0.846 3.2E-52
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 2 0 2008 2011
Entrez Id: 7372
Gene Symbol: UMPS
UMPS
uridine monophosphate synthetase 0.584 0.615 1.1E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.350 None 1.000 2 0 2003 2013
Entrez Id: 5426
Gene Symbol: POLE
POLE
DNA polymerase epsilon, catalytic subunit 0.526 0.731 8.0E-27
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 2 0 2013 2016
Entrez Id: 2977
Gene Symbol: GUCY1A2
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2 0.792 0.192 0.31
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 2 0 2008 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.340 None 1.000 2 0 2002 2013
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.340 None 1.000 2 0 2006 2011
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
toll like receptor 2 0.361 0.923 1.0E-06
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.320 None 1.000 2 0 2006 2010
Entrez Id: 7087
Gene Symbol: ICAM5
ICAM5
intercellular adhesion molecule 5 0.716 0.346 2.1E-03
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 2 0 2008 2011
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
thymidine phosphorylase 0.495 0.769 1.2E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.370 None 1.000 2 0 1998 2007
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
transcription factor 7 like 2 0.485 0.846 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.490 None 1.000 2 0 2002 2019