Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2875
Gene Symbol: GPT
GPT
glutamic--pyruvic transaminase 0.403 0.923 3.6E-19
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 2 0 1977 2020
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
interferon alpha 2 0.442 0.885
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 1 0 1991 1991
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 1993 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.350 None 0.818 6 0 1995 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.330 None 1.000 2 0 1995 2019
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
keratin 18 0.530 0.692 0.73
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 1997 2017
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 2 0 2001 2019
Entrez Id: 3589
Gene Symbol: IL11
IL11
interleukin 11 0.481 0.808 3.2E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 1 0 2001 2001
Entrez Id: 2946
Gene Symbol: GSTM2
GSTM2
glutathione S-transferase mu 2 0.488 0.808 3.4E-07
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.350 None 1.000 1 0 2001 2014
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
C-X-C motif chemokine ligand 10 0.378 0.885 0.37
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2001 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2001 2019
Entrez Id: 10
Gene Symbol: NAT2
NAT2
N-acetyltransferase 2 0.451 0.885 3.3E-06
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 4 0 2002 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 2 0 2002 2011
Entrez Id: 6649
Gene Symbol: SOD3
SOD3
superoxide dismutase 3 0.531 0.808 7.2E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 1 0 2002 2002
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 0.889 4 0 2003 2020
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19
cytochrome P450 family 2 subfamily C member 19 0.467 0.846 6.5E-20
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 2 0 2003 2018
Entrez Id: 6652
Gene Symbol: SORD
SORD
sorbitol dehydrogenase 0.552 0.769 4.5E-08
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 1 0 2003 2003
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
nuclear receptor subfamily 1 group H member 4 0.513 0.808 9.4E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 1 0 2003 2003
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
cytochrome P450 family 2 subfamily C member 9 0.506 0.885 1.3E-10
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 3 0 2004 2018
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
nuclear receptor subfamily 1 group I member 3 0.448 0.846 3.5E-08
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 3 0 2004 2019
Entrez Id: 50616
Gene Symbol: IL22
IL22
interleukin 22 0.393 0.885 1.9E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 3 0 2004 2013
Entrez Id: 686
Gene Symbol: BTD
BTD
biotinidase 0.628 0.654 1.5E-07
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 1 0 2004 2004
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.330 None 0.833 3 0 2005 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.360 None 1.000 2 0 2005 2019
Entrez Id: 3242
Gene Symbol: HPD
HPD
4-hydroxyphenylpyruvate dioxygenase 0.573 0.769 5.3E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.300 None 1.000 2 0 2005 2012