Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 400916
Gene Symbol: CHCHD10
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10 0.623 0.462 5.4E-06
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 0.955 7 0 2014 2020
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
sequestosome 1 0.428 0.885 8.6E-04
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 0.974 4 0 2009 2020
Entrez Id: 5216
Gene Symbol: PFN1
PFN1
profilin 1 0.565 0.769 0.73
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 1.000 3 0 2012 2019
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B
charged multivesicular body protein 2B 0.543 0.731 4.6E-06
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.680 None 1.000 3 0 2006 2016
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 0.929 2 0 2007 2019
Entrez Id: 5445
Gene Symbol: PON2
PON2
paraoxonase 2 0.566 0.808 5.4E-05
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.400 None 1.000 2 0 2010 2013
Entrez Id: 5446
Gene Symbol: PON3
PON3
paraoxonase 3 0.663 0.692 2.1E-07
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.400 None 1.000 2 0 2010 2013
Entrez Id: 23025
Gene Symbol: UNC13A
UNC13A
unc-13 homolog A 0.705 0.423 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 1.000 2 0 2009 2019
Entrez Id: 55830
Gene Symbol: GLT8D1
GLT8D1
glycosyltransferase 8 domain containing 1 0.711 0.462 1.1E-08
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.430 None 1.000 1 0 2019 2020
Entrez Id: 4744
Gene Symbol: NEFH
NEFH
neurofilament heavy 0.588 0.769 2.7E-12
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 1.000 1 0 1993 2018
Entrez Id: 4750
Gene Symbol: NEK1
NEK1
NIMA related kinase 1 0.575 0.769 1.9E-25
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.680 None 1.000 1 0 2016 2019
Entrez Id: 9217
Gene Symbol: VAPB
VAPB
VAMP associated protein B and C 0.666 0.423 0.58
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 0.967 1 0 2004 2019
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
triggering receptor expressed on myeloid cells 2 0.519 0.769 3.3E-09
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 0.833 1 0 2013 2019
Entrez Id: 899
Gene Symbol: CCNF
CCNF
cyclin F 0.700 0.615 0.13
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.460 None 1.000 1 0 2016 2019
Entrez Id: 755
Gene Symbol: CFAP410
CFAP410
cilia and flagella associated protein 410 0.633 0.615 3.3E-07
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.620 None 1.000 1 0 2016 2019
Entrez Id: 7415
Gene Symbol: VCP
VCP
valosin containing protein 0.469 0.923 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 0.962 1 0 2008 2020
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
ataxin 2 0.482 0.808 0.85
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 0.971 1 0 2006 2019
Entrez Id: 10133
Gene Symbol: OPTN
OPTN
optineurin 0.548 0.808 5.9E-18
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 0.954 1 0 2010 2020
Entrez Id: 3178
Gene Symbol: HNRNPA1
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1 0.529 0.885 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 1.000 1 0 2013 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.490 None 1.000 1 0 2007 2018
Entrez Id: 1639
Gene Symbol: DCTN1
DCTN1
dynactin subunit 1 0.597 0.500 8.4E-02
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 0.909 1 0 2005 2019
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4
EPH receptor A4 0.566 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.500 None 0.909 1 0 2012 2019
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
erb-b2 receptor tyrosine kinase 4 0.455 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.430 None 1.000 1 0 2013 2019
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
TAR DNA binding protein 0.493 0.808 0.99
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 0.979 1 0 2006 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS
FUS RNA binding protein 0.470 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.700 None 0.981 1 0 2009 2020