Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
neuregulin 1 0.506 0.759 1.00
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.500 0.964 38 0 2002 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT
catechol-O-methyltransferase 0.426 0.897 1.3E-05
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.923 32 0 1984 2018
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
DISC1 scaffold protein 0.592 0.552 1.7E-06
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.970 23 0 2001 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.942 22 0 1999 2018
Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
dystrobrevin binding protein 1 0.619 0.379 5.0E-06
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.921 21 0 2002 2018
Entrez Id: 267012
Gene Symbol: DAOA
DAOA
D-amino acid oxidase activator 0.681 0.172 1.6E-04
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.878 20 0 2002 2018
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
dopamine receptor D2 0.454 0.724 0.79
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.917 20 0 1991 2018
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
dopamine receptor D3 0.527 0.552 2.0E-03
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.908 14 0 1993 2016
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
5-hydroxytryptamine receptor 2A 0.488 0.759 0.48
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.926 14 0 1992 2016
Entrez Id: 5999
Gene Symbol: RGS4
RGS4
regulator of G protein signaling 4 0.685 0.345 5.4E-08
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.100 0.886 12 0 2001 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.354 0.828 1.2E-09
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.500 0.868 11 0 1997 2018
Entrez Id: 2913
Gene Symbol: GRM3
GRM3
glutamate metabotropic receptor 3 0.627 0.414 0.81
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.500 0.946 9 0 2002 2018
Entrez Id: 4855
Gene Symbol: NOTCH4
NOTCH4
notch 4 0.564 0.655 1.8E-22
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.500 0.750 9 0 2000 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.938 8 0 1997 2014
Entrez Id: 5649
Gene Symbol: RELN
RELN
reelin 0.547 0.655 1.00
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.500 0.941 7 0 1999 2017
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
solute carrier family 6 member 4 0.446 0.724 0.26
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.900 7 0 1998 2016
Entrez Id: 282706
Gene Symbol: DAOA-AS1
DAOA-AS1
DAOA antisense RNA 1 0.713 0.138
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 1.000 7 0 2004 2014
Entrez Id: 9722
Gene Symbol: NOS1AP
NOS1AP
nitric oxide synthase 1 adaptor protein 0.652 0.345 0.62
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.500 1.000 6 0 2005 2016
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
glutamate decarboxylase 1 0.542 0.724 6.6E-02
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.963 6 0 2000 2016
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
cholinergic receptor nicotinic alpha 7 subunit 0.550 0.552 1.5E-03
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.750 6 0 1998 2016
Entrez Id: 1610
Gene Symbol: DAO
DAO
D-amino acid oxidase 0.667 0.414 9.7E-22
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.947 6 0 2002 2018
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
glycogen synthase kinase 3 beta 0.488 0.793 0.96
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 1.000 6 0 2003 2017
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B 0.561 0.483 1.00
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.917 5 0 2000 2016
Entrez Id: 5533
Gene Symbol: PPP3CC
PPP3CC
protein phosphatase 3 catalytic subunit gamma 0.815 0.103 0.17
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 1.000 5 0 2003 2015
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
dopamine receptor D4 0.536 0.414 7.1E-09
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.400 0.729 5 0 1994 2015