Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 1.000 None 0.983 55 0 1986 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 strong 0.950 54 0 1994 2020
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
melanocortin 1 receptor 0.524 0.808 8.1E-11
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.959 17 0 1996 2020
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.969 16 0 1987 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.943 15 0 1991 2020
Entrez Id: 4286
Gene Symbol: MITF
MITF
melanocyte inducing transcription factor 0.499 0.808 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.974 13 0 2002 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.986 11 0 1996 2020
Entrez Id: 7299
Gene Symbol: TYR
TYR
tyrosinase 0.473 0.808 5.0E-32
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.984 10 0 1988 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 0.981 10 0 1994 2019
Entrez Id: 8190
Gene Symbol: MIA
MIA
MIA SH3 domain containing 0.537 0.769 1.7E-05
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 0.975 8 0 1991 2019
Entrez Id: 317
Gene Symbol: APAF1
APAF1
apoptotic peptidase activating factor 1 0.525 0.769 9.6E-06
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 0.933 8 0 2001 2019
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene, receptor tyrosine kinase 0.366 0.808 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.967 8 0 1992 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 0.943 8 0 1996 2020
Entrez Id: 2315
Gene Symbol: MLANA
MLANA
melan-A 0.579 0.692 1.3E-09
CUI: C0025202
Disease: melanoma
melanoma
disease 0.400 None 0.982 7 0 1994 2020
Entrez Id: 3685
Gene Symbol: ITGAV
ITGAV
integrin subunit alpha V 0.526 0.769 2.3E-04
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 1.000 7 0 1989 2016
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
fibroblast growth factor 2 0.383 0.923 1.8E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 0.976 7 0 1989 2019
Entrez Id: 5925
Gene Symbol: RB1
RB1
RB transcriptional corepressor 1 0.444 0.885 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.090 None 1.000 7 0 1996 2018
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.200 None 1.000 7 0 2004 2020
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
nuclear factor kappa B subunit 1 0.396 0.923 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 1.000 7 0 2004 2020
Entrez Id: 1000
Gene Symbol: CDH2
CDH2
cadherin 2 0.535 0.731 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.080 None 1.000 6 0 2000 2017
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
cyclin dependent kinase 4 0.412 0.808 6.3E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 strong 0.961 6 0 1994 2020
Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
integrin subunit beta 1 0.496 0.808 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.080 None 1.000 6 0 2000 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.400 None 1.000 6 0 2001 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 0.976 6 0 1991 2020
Entrez Id: 11009
Gene Symbol: IL24
IL24
interleukin 24 0.498 0.769 5.9E-07
CUI: C0025202
Disease: melanoma
melanoma
disease 0.100 None 1.000 5 0 1995 2019