Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 334
Gene Symbol: APLP2
APLP2
amyloid beta precursor like protein 2 0.659 0.462 0.38
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.260 None 1.000 1 0 1994 2012
Entrez Id: 58157
Gene Symbol: NGB
NGB
neuroglobin 0.631 0.462 4.5E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 1.000 1 0 2007 2019
Entrez Id: 723961
Gene Symbol: INS-IGF2
INS-IGF2
INS-IGF2 readthrough 0.633 0.500 5.6E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.210 None 1.000 1 0 2002 2007
Entrez Id: 3416
Gene Symbol: IDE
IDE
insulin degrading enzyme 0.604 0.577 6.6E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 None 0.955 4 0 2000 2019
Entrez Id: 599
Gene Symbol: BCL2L2
BCL2L2
BCL2 like 2 0.599 0.615 0.47
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.210 None 1.000 1 0 2004 2010
Entrez Id: 8754
Gene Symbol: ADAM9
ADAM9
ADAM metallopeptidase domain 9 0.560 0.654 2.9E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.210 None 1.000 1 0 2011 2014
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
phospholipase C beta 1 0.595 0.654 0.98
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.200 None 0 0
Entrez Id: 1759
Gene Symbol: DNM1
DNM1
dynamin 1 0.595 0.692 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.260 None 1.000 1 0 2003 2020
Entrez Id: 4133
Gene Symbol: MAP2
MAP2
microtubule associated protein 2 0.537 0.692 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 1.000 1 0 1991 2019
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
ATP synthase F1 subunit alpha 0.604 0.731 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.540 None 1.000 1 0 2003 2017
Entrez Id: 10519
Gene Symbol: CIB1
CIB1
calcium and integrin binding 1 0.458 0.769 3.3E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.230 None 1.000 1 0 2005 2017
Entrez Id: 23621
Gene Symbol: BACE1
BACE1
beta-secretase 1 0.559 0.769 0.88
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 None 0.985 1 0 1999 2020
Entrez Id: 3297
Gene Symbol: HSF1
HSF1
heat shock transcription factor 1 0.507 0.769 0.75
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.250 None 1.000 1 0 2013 2018
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
insulin receptor substrate 1 0.488 0.769 2.4E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 1.000 1 0 2009 2019
Entrez Id: 4035
Gene Symbol: LRP1
LRP1
LDL receptor related protein 1 0.482 0.769 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 0.935 1 0 1996 2019
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
ATPase copper transporting alpha 0.494 0.769 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.210 None 1.000 1 0 2009 2015
Entrez Id: 5300
Gene Symbol: PIN1
PIN1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.488 0.769 0.74
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 0.979 0 0 2001 2019
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
caspase 12 (gene/pseudogene) 0.638 0.808 1.3E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.200 None 1.000 1 0 2018 2018
Entrez Id: 1103
Gene Symbol: CHAT
CHAT
choline O-acetyltransferase 0.520 0.808 5.6E-11
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 0.981 1 0 1987 2019
Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH
glyceraldehyde-3-phosphate dehydrogenase 0.447 0.808 0.11
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 0.895 1 0 1994 2018
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
heat shock protein family B (small) member 1 0.436 0.808 2.8E-07
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.230 None 1.000 1 0 2011 2019
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
heat shock protein family D (Hsp60) member 1 0.432 0.808 0.99
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.240 None 1.000 1 0 2002 2018
Entrez Id: 4311
Gene Symbol: MME
MME
membrane metalloendopeptidase 0.407 0.808 1.5E-18
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 0.955 1 0 2001 2020
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
metallothionein 2A 0.553 0.808 1.2E-05
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.210 None 1.000 1 0 2006 2019
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
neurotrophic receptor tyrosine kinase 2 0.479 0.808 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.290 None 0.900 1 0 1997 2019