Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.600 None 0.984 80 0 1994 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.800 None 0.974 43 0 1990 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 18 0 1994 2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 17 0 2002 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.800 None 1.000 14 0 1997 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.600 None 0.974 13 0 1991 2019
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
cytochrome P450 family 1 subfamily A member 1 0.436 0.846 1.1E-17
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 13 0 1994 2018
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
glutathione S-transferase pi 1 0.383 0.923 1.4E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.600 None 1.000 12 0 2002 2009
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 11 0 1992 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 11 0 1999 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
X-ray repair cross complementing 1 0.421 0.923 6.3E-09
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 10 0 2002 2010
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Ras association domain family member 1 0.420 0.808 4.9E-06
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 10 0 2000 2018
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit 0.420 0.846 7.1E-20
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 9 0 2002 2010
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
glutathione S-transferase theta 1 0.393 0.923 1.5E-04
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.390 None 1.000 9 0 2002 2008
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
fragile histidine triad diadenosine triphosphatase 0.444 0.846 5.7E-03
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 9 0 1996 2013
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.362 0.846 1.00
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 9 0 1995 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 9 0 2002 2018
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
baculoviral IAP repeat containing 5 0.495 0.731 5.6E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.390 None 1.000 9 0 2004 2009
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 8 0 1999 2013
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit 0.445 0.846 1.6E-07
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.580 None 1.000 8 0 2003 2018
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 8 0 2004 2015
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.374 0.846 0.99
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.400 None 1.000 8 0 2000 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.100 None 1.000 7 0 2002 2018
Entrez Id: 4353
Gene Symbol: MPO
MPO
myeloperoxidase 0.377 0.923 7.1E-15
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.370 None 1.000 7 0 2002 2008
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
group 0.500 None 1.000 7 0 2003 2019