Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 49 0 1997 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.983 41 0 1990 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.989 35 0 1991 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.978 26 0 2002 2019
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.900 None 0.982 25 0 1990 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 22 0 1999 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.985 21 0 1997 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.406 0.808 0.90
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 20 0 1996 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 0.957 19 0 2002 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.600 None 1.000 18 0 1998 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.200 None 1.000 16 0 2003 2016
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
mutY DNA glycosylase 0.521 0.769 1.3E-18
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 1.000 15 0 2002 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.401 0.808 0.15
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.950 15 0 1999 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.976 15 0 2003 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.300 None 1.000 14 0 2002 2013
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 13 0 2002 2014
Entrez Id: 10
Gene Symbol: NAT2
NAT2
N-acetyltransferase 2 0.451 0.885 3.3E-06
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 1.000 9 0 1996 2008
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 1.000 9 0 1999 2013
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 1.000 9 0 1996 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 9 0 1999 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
mutS homolog 6 0.462 0.731 3.7E-05
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 1.000 8 0 1997 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.200 None 1.000 8 0 2002 2016
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
dihydropyrimidine dehydrogenase 0.493 0.846 3.4E-22
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.600 None 0.952 8 0 1999 2016
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
cyclin dependent kinase inhibitor 1A 0.403 0.769 1.9E-03
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.100 None 1.000 8 0 1996 2008
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
matrix metallopeptidase 1 0.385 0.885 7.7E-18
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.380 None 1.000 8 0 2002 2013