Source: ORPHANET

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		TAR DNA binding protein 0.493 0.808 0.99
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.979 1 0 2006 2020
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		ataxin 2 0.482 0.808 0.85
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.971 1 0 2006 2019
Entrez Id: 2043
Gene Symbol: EPHA4
EPHA4 		EPH receptor A4 0.566 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.909 1 0 2012 2019
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		erb-b2 receptor tyrosine kinase 4 0.455 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.430 None 1.000 1 0 2013 2019
Entrez Id: 2521
Gene Symbol: FUS
FUS 		FUS RNA binding protein 0.470 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.981 1 0 2009 2020
Entrez Id: 29110
Gene Symbol: TBK1
TBK1 		TANK binding kinase 1 0.513 0.846 7.5E-02
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 strong 1.000 1 0 2015 2019
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1 		sequestosome 1 0.428 0.885 8.6E-04
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.974 4 0 2009 2020
Entrez Id: 5444
Gene Symbol: PON1
PON1 		paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.929 2 0 2007 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.490 None 1.000 1 0 2007 2018
Entrez Id: 3178
Gene Symbol: HNRNPA1
HNRNPA1 		heterogeneous nuclear ribonucleoprotein A1 0.529 0.885 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 1.000 1 0 2013 2019
Entrez Id: 7415
Gene Symbol: VCP
VCP 		valosin containing protein 0.469 0.923 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.962 1 0 2008 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		superoxide dismutase 1 0.379 0.962 0.18
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.800 strong 0.985 1 0 1993 2020