Source: ORPHANET

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 311
Gene Symbol: ANXA11
ANXA11 		annexin A11 0.650 0.692 4.7E-10
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.440 None 1.000 1 0 2017 2019
Entrez Id: 3178
Gene Symbol: HNRNPA1
HNRNPA1 		heterogeneous nuclear ribonucleoprotein A1 0.529 0.885 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 1.000 1 0 2013 2019
Entrez Id: 400916
Gene Symbol: CHCHD10
CHCHD10 		coiled-coil-helix-coiled-coil-helix domain containing 10 0.623 0.462 5.4E-06
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.955 7 0 2014 2020
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1 		sequestosome 1 0.428 0.885 8.6E-04
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.974 4 0 2009 2020
Entrez Id: 7415
Gene Symbol: VCP
VCP 		valosin containing protein 0.469 0.923 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.962 1 0 2008 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		superoxide dismutase 1 0.379 0.962 0.18
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.800 strong 0.985 1 0 1993 2020
Entrez Id: 55830
Gene Symbol: GLT8D1
GLT8D1 		glycosyltransferase 8 domain containing 1 0.711 0.462 1.1E-08
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.430 None 1.000 1 0 2019 2020
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		C9orf72-SMCR8 complex subunit 0.496 0.769 1.1E-06
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.800 limited 0.985 1 0 2009 2020
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		TAR DNA binding protein 0.493 0.808 0.99
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.979 1 0 2006 2020
Entrez Id: 29978
Gene Symbol: UBQLN2
UBQLN2 		ubiquilin 2 0.656 0.462 0.85
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.980 1 0 2011 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS 		FUS RNA binding protein 0.470 0.846 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.981 1 0 2009 2020
Entrez Id: 10133
Gene Symbol: OPTN
OPTN 		optineurin 0.548 0.808 5.9E-18
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.954 1 0 2010 2020