Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP
amyloid beta precursor protein 0.430 0.862 6.2E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.900 0.967 6 0 1987 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
presenilin 1 0.490 0.690 0.98
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 0.939 6 0 1990 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.352 0.931 1.7E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 0.922 2 0 1991 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 1.000 4 0 1996 2016
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.976 2 0 1992 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.312 0.931 0.13
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.946 1 0 1989 2017
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
glycogen synthase kinase 3 beta 0.488 0.793 0.96
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.919 1 0 2000 2016
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.367 0.897 1.6E-37
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.859 1 0 1998 2018
Entrez Id: 3643
Gene Symbol: INSR
INSR
insulin receptor 0.459 0.724 2.0E-05
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.590 1.000 1 0 2002 2016
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
plasminogen activator, urokinase 0.434 0.690 2.1E-06
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.580 1.000 10 0 1994 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.400 0.793 0.39
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.580 1.000 1 0 2005 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
insulin like growth factor 2 0.399 0.828 4.7E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.550 1.000 1 0 2002 2015
Entrez Id: 4852
Gene Symbol: NPY
NPY
neuropeptide Y 0.469 0.690 0.16
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.550 0.600 1 0 2000 2016
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
insulin like growth factor 1 receptor 0.433 0.828 0.99
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.520 1.000 2 0 2005 2013
Entrez Id: 3630
Gene Symbol: INS
INS
insulin 0.458 0.828 0.32
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.520 1.000 1 0 1991 2007
Entrez Id: 581
Gene Symbol: BAX
BAX
BCL2 associated X, apoptosis regulator 0.450 0.862 0.30
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.510 1.000 3 0 1997 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 0.929 1 0 1993 2017
Entrez Id: 4311
Gene Symbol: MME
MME
membrane metalloendopeptidase 0.461 0.690 7.0E-17
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 0.964 2 0 1995 2016
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.406 0.931 0.13
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 1.000 1 0 1989 2016
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
nerve growth factor receptor 0.508 0.724 0.30
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 0.889 1 0 1989 2016
Entrez Id: 5300
Gene Symbol: PIN1
PIN1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.536 0.655 0.76
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 0.964 1 0 2001 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 0.952 1 0 1998 2015
Entrez Id: 6285
Gene Symbol: S100B
S100B
S100 calcium binding protein B 0.443 0.862 4.7E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 1.000 1 0 1996 2011
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.426 0.862 0.76
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 0.944 1 0 1990 2017
Entrez Id: 1103
Gene Symbol: CHAT
CHAT
choline O-acetyltransferase 0.559 0.655 4.9E-11
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 0.964 1 0 1987 2014