Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.500 0.947 18 0 1986 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 1.000 13 0 1996 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 1.000 11 0 1998 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.298 0.897 2.7E-05
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 0.889 10 0 1998 2015
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.388 0.828 0.14
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 0.750 8 0 2003 2010
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
cyclin dependent kinase inhibitor 1A 0.415 0.724 2.1E-03
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 1.000 8 0 2002 2010
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 0.923 6 0 1994 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 1.000 6 0 1991 2016
Entrez Id: 324
Gene Symbol: APC
APC
APC, WNT signaling pathway regulator 0.397 0.828 1.00
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 0.931 5 0 1990 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 0.941 3 0 1988 2015
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.457 0.759 0.76
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.400 1.000 2 0 1988 2009
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.380 1.000 3 0 1998 2009
Entrez Id: 581
Gene Symbol: BAX
BAX
BCL2 associated X, apoptosis regulator 0.450 0.862 0.30
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.370 1.000 4 0 1997 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.354 0.828 1.2E-09
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.370 1.000 4 0 2002 2011
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
nuclear factor kappa B subunit 1 0.365 0.931 1.00
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.360 1.000 3 0 2005 2014
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
prominin 1 0.450 0.793 2.4E-18
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.350 0.500 3 0 2007 2013
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
TNF superfamily member 10 0.440 0.828 0.13
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.350 1.000 1 0 2002 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.350 1.000 1 0 1992 2016
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
baculoviral IAP repeat containing 5 0.479 0.655 5.7E-02
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 4 0 2004 2009
Entrez Id: 6714
Gene Symbol: SRC
SRC
SRC proto-oncogene, non-receptor tyrosine kinase 0.502 0.690 1.00
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 4 0 2003 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.339 0.862 7.0E-18
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 1.000 3 0 2005 2007
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 1.000 2 0 2008 2012
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
matrix metallopeptidase 7 0.470 0.724 1.1E-09
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 1.000 2 0 1999 2008
Entrez Id: 8549
Gene Symbol: LGR5
LGR5
leucine rich repeat containing G protein-coupled receptor 5 0.598 0.448 2.0E-08
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 1.000 1 0 2007 2015
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
axin 2 0.570 0.552 0.66
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms
group 0.340 1.000 1 0 2002 2014