Source: CTD_human

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
APC, WNT signaling pathway regulator 0.397 0.828 1.00
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.600 0.937 7 0 1990 2018
Entrez Id: 1630
Gene Symbol: DCC
DCC
DCC netrin 1 receptor 0.504 0.655 0.99
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.600 0.906 1 0 1990 2015
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.457 0.759 0.76
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.919 11 0 1997 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.354 0.828 1.2E-09
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.914 8 0 1997 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.946 8 0 1989 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.971 6 0 1998 2018
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
dihydropyrimidine dehydrogenase 0.520 0.690 5.7E-22
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.967 5 0 1998 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 4 0 1998 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.970 4 0 2002 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.430 0.759 1.00
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.981 3 0 1996 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.963 3 0 1992 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.967 3 0 1993 2018
Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2
secreted frizzled related protein 2 0.579 0.517 2.0E-03
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 2 0 2004 2018
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
secreted frizzled related protein 1 0.500 0.759 0.97
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.923 2 0 2002 2015
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group) 0.449 0.793 1.3E-32
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.900 2 0 2004 2018
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
transcription factor 7 like 2 0.538 0.621 0.99
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.880 2 0 2002 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE
DNA polymerase epsilon, catalytic subunit 0.616 0.345 1.8E-25
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 2 0 2013 2018
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
thymidine phosphorylase 0.513 0.655 7.2E-05
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 2 0 1996 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.956 2 0 1992 2018
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.371 0.828 1.3E-05
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.923 2 0 1990 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.373 0.862 0.84
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 2 0 1992 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.432 0.759 0.11
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.964 2 0 1999 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.359 0.931 5.6E-09
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 0.786 2 0 2006 2016
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2
cytochrome P450 family 1 subfamily A member 2 0.509 0.828 2.2E-10
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 1 0 1993 2015
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.400 1.000 1 0 1989 2017