Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.367 0.897 1.6E-37
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.954 3 0 1992 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.931 2 0 1996 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 1.000 2 0 2000 2018
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.567 0.552 9.1E-06
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.909 1 0 1991 2016
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.546 0.690 6.4E-04
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.900 1 0 1989 2015
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
angiotensin II receptor type 1 0.454 0.759 5.7E-04
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 1.000 1 0 1997 2016
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.406 0.862 3.9E-08
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.962 1 0 1992 2018
Entrez Id: 156
Gene Symbol: GRK2
GRK2
G protein-coupled receptor kinase 2 0.580 0.517
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.889 1 0 1994 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.417 0.828 0.46
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 1.000 1 0 1994 2010
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
adrenoceptor beta 1 0.586 0.586 3.5E-06
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.600 0.935 1 0 1992 2016
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 0.572 0.552 1.00
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.570 0.857 1 0 1996 2016
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.367 0.793 0.97
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.550 1.000 1 0 2005 2016
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
PPARG coactivator 1 alpha 0.497 0.828 1.00
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.550 1.000 0 0 2004 2013
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
myostatin 0.602 0.586 0.44
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.540 1.000 1 0 2007 2015
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.403 0.862 7.9E-03
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.530 1.000 1 0 2005 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.396 0.897 0.16
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.520 1.000 0 0 2006 2014
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
adrenoceptor beta 3 0.558 0.552 2.7E-07
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.510 1.000 1 0 2004 2011
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
5-hydroxytryptamine receptor 2B 0.696 0.310 3.5E-10
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.500 1 0 2008 2009
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Rac family small GTPase 1 0.470 0.931 0.71
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.500 1 0 2003 2006
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
myosin heavy chain 7 0.564 0.483 3.7E-16
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.320 1.000 1 0 2008 2014
Entrez Id: 4624
Gene Symbol: MYH6
MYH6
myosin heavy chain 6 0.621 0.552 3.2E-31
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.320 1.000 1 0 1997 2015
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
adrenoceptor beta 2 0.479 0.793 0.58
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.300 0.952 2 0 1996 2013
Entrez Id: 5350
Gene Symbol: PLN
PLN
phospholamban 0.627 0.379 0.47
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.300 0.893 2 0 1991 2018
Entrez Id: 6262
Gene Symbol: RYR2
RYR2
ryanodine receptor 2 0.575 0.414 1.00
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.300 1.000 1 0 2002 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
disease 0.300 1.000 1 0 1999 2014