Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.388 0.828 0.14
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.700 0.926 3 0 1999 2016
Entrez Id: 490
Gene Symbol: ATP2B1
ATP2B1
ATPase plasma membrane Ca2+ transporting 1 0.707 0.379 1.00
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.700 0.938 1 0 1999 2017
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
nuclear receptor subfamily 3 group C member 1 0.427 0.793 0.98
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.700 0.700 1 0 1993 2016
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2
hydroxysteroid 11-beta dehydrogenase 2 0.551 0.724 9.1E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.700 0.900 1 0 1995 2016
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.463 0.759 5.5E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.670 1.000 1 0 2002 2016
Entrez Id: 1889
Gene Symbol: ECE1
ECE1
endothelin converting enzyme 1 0.580 0.483 0.96
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.630 1.000 2 0 2000 2014
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.406 0.862 3.9E-08
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.942 6 0 1980 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.367 0.897 1.6E-37
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.852 4 0 1986 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.401 0.862 8.9E-07
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.924 4 0 1996 2018
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
angiotensin II receptor type 1 0.454 0.759 5.7E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.898 4 0 1994 2017
Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
angiotensin II receptor type 2 0.554 0.621 8.2E-03
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 3 0 2001 2016
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.367 0.793 0.97
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.857 2 0 2002 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.336 0.931 0.17
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 2 0 1996 2016
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
cytochrome b-245 alpha chain 0.550 0.655 1.1E-05
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.813 2 0 2002 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 2 0 1998 2016
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
angiotensin I converting enzyme 2 0.542 0.655 1.00
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.966 2 0 2004 2017
Entrez Id: 118
Gene Symbol: ADD1
ADD1
adducin 1 0.607 0.517 0.99
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.871 2 0 1995 2016
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
endothelin receptor type A 0.469 0.828 0.99
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 2 0 1994 2016
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.417 0.828 0.46
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.943 2 0 1993 2017
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.567 0.552 9.1E-06
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.875 1 0 1997 2016
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.400 0.793 0.39
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.931 1 0 1998 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.339 0.862 7.0E-18
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 1 0 2004 2016
Entrez Id: 3816
Gene Symbol: KLK1
KLK1
kallikrein 1 0.564 0.552 1.1E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 1 0 1995 2013
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.373 0.862 0.84
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 1.000 1 0 1999 2017
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.546 0.690 6.4E-04
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
group 0.600 0.952 1 0 1989 2018