Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 1.000 0.972 55 0 1986 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 strong 0.940 54 0 1994 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 0.954 4 0 1997 2017
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.420 0.690 0.53
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.956 16 0 1988 2018
Entrez Id: 4286
Gene Symbol: MITF
MITF
melanogenesis associated transcription factor 0.526 0.690 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.969 13 0 1996 2018
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
cyclin dependent kinase 4 0.449 0.724 7.8E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 strong 0.957 6 0 1994 2018
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
mitogen-activated protein kinase kinase 1 0.459 0.759 0.91
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.893 2 0 2003 2018
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ
G protein subunit alpha q 0.586 0.483 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 1 0 1989 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.467 0.655 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 1 0 1999 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Rac family small GTPase 1 0.470 0.931 0.71
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 1 0 2004 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0025202
Disease: melanoma
melanoma
disease 0.600 0.940 15 0 1991 2018
Entrez Id: 4763
Gene Symbol: NF1
NF1
neurofibromin 1 0.458 0.724 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.600 1.000 1 0 1993 2017
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
melanocortin 1 receptor 0.570 0.586 6.6E-11
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.959 17 0 1997 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.889 11 0 1996 2015
Entrez Id: 7299
Gene Symbol: TYR
TYR
tyrosinase 0.505 0.724 4.3E-32
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.965 10 0 1985 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene receptor tyrosine kinase 0.394 0.759 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.978 8 0 1992 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.984 4 0 2002 2018
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit 0.447 0.828 1.7E-20
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 1.000 2 0 2001 2016
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.462 0.793 0.89
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 1.000 2 0 2003 2017
Entrez Id: 51151
Gene Symbol: SLC45A2
SLC45A2
solute carrier family 45 member 2 0.619 0.448 2.0E-06
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 1.000 2 0 2002 2017
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.443 0.793 2.8E-06
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 1.000 1 0 2000 2015
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
methylthioadenosine phosphorylase 0.554 0.586 6.7E-08
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.917 1 0 1994 2018
Entrez Id: 2315
Gene Symbol: MLANA
MLANA
melan-A 0.648 0.517 1.4E-09
CUI: C0025202
Disease: melanoma
melanoma
disease 0.400 0.960 7 0 1995 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.400 0.958 6 0 2001 2018
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
heparanase 0.464 0.759 2.2E-14
CUI: C0025202
Disease: melanoma
melanoma
disease 0.400 1.000 5 0 1999 2016