Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 0.898 13 0 1991 2018
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.391 0.897 1.4E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.987 24 0 2001 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.298 0.897 2.7E-05
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.951 23 0 1994 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.339 0.862 7.0E-18
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.974 18 0 1996 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.932 17 0 1989 2018
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
heparanase 0.464 0.759 2.2E-14
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.959 15 0 1999 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.373 0.862 0.84
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.979 15 0 1993 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.432 0.759 0.11
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.969 15 0 1993 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.931 14 0 1998 2018
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.421 0.724 0.13
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.978 11 0 2001 2018
Entrez Id: 4830
Gene Symbol: NME1
NME1
NME/NM23 nucleoside diphosphate kinase 1 0.470 0.759 3.1E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.915 10 0 1989 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.944 9 0 1989 2018
Entrez Id: 7430
Gene Symbol: EZR
EZR
ezrin 0.533 0.690 0.45
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.942 6 0 1999 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.875 6 0 2001 2017
Entrez Id: 3732
Gene Symbol: CD82
CD82
CD82 molecule 0.533 0.586 9.9E-09
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.957 6 0 1995 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.953 5 0 1992 2018
Entrez Id: 389
Gene Symbol: RHOC
RHOC
ras homolog family member C 0.656 0.310 0.76
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 1.000 5 0 2003 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.336 0.931 0.17
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.985 5 0 1995 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.391 0.862 1.0E-06
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.993 4 0 1996 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.975 4 0 1997 2018
Entrez Id: 3082
Gene Symbol: HGF
HGF
hepatocyte growth factor 0.394 0.793 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.981 4 0 1994 2018
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR
plasminogen activator, urokinase receptor 0.561 0.586 6.1E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 1.000 4 0 1998 2015
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
twist family bHLH transcription factor 1 0.464 0.759 0.36
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.962 4 0 2004 2018
Entrez Id: 25855
Gene Symbol: BRMS1
BRMS1
BRMS1, transcriptional repressor and anoikis regulator 0.633 0.448 1.6E-07
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.946 4 0 2000 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.389 0.862 2.1E-07
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 0.948 4 0 1990 2018