Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.991 18 0 1996 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.970 17 0 1989 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.983 15 0 1993 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.968 14 0 1998 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.936 13 0 1991 2020
Entrez Id: 3732
Gene Symbol: CD82
CD82
CD82 molecule 0.507 0.731 1.3E-08
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.600 None 0.973 6 0 1995 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.989 24 0 2000 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.976 23 0 1994 2020
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
heparanase 0.425 0.808 2.3E-14
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.972 15 0 1999 2020
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.401 0.808 0.15
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.960 15 0 1993 2020
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.995 11 0 2000 2020
Entrez Id: 4830
Gene Symbol: NME1
NME1
NME/NM23 nucleoside diphosphate kinase 1 0.443 0.808 3.2E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.940 10 0 1989 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.973 9 0 1988 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.962 6 0 1996 2020
Entrez Id: 7430
Gene Symbol: EZR
EZR
ezrin 0.476 0.808 0.18
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.975 6 0 1999 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.962 5 0 1992 2020
Entrez Id: 389
Gene Symbol: RHOC
RHOC
ras homolog family member C 0.641 0.308 0.77
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 5 0 2003 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.982 5 0 1994 2020
Entrez Id: 3082
Gene Symbol: HGF
HGF
hepatocyte growth factor 0.374 0.885 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.986 4 0 1993 2019
Entrez Id: 25855
Gene Symbol: BRMS1
BRMS1
BRMS1 transcriptional repressor and anoikis regulator 0.597 0.615 1.6E-07
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 4 0 2000 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.989 4 0 1996 2020
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.979 4 0 1990 2020
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR
plasminogen activator, urokinase receptor 0.536 0.731 5.3E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 4 0 1998 2017
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
twist family bHLH transcription factor 1 0.397 0.846 0.34
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.980 4 0 2004 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.976 4 0 1997 2020