Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.900 1.000 7 0 1993 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.700 1.000 8 0 1996 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.700 1.000 7 0 1993 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.430 0.759 1.00
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.700 0.923 4 0 1998 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2, DNA repair associated 0.426 0.793 5.5E-24
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.540 1.000 2 0 2003 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1, DNA repair associated 0.410 0.862 1.8E-28
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.520 2 0 2005 2015
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1
serine peptidase inhibitor, Kazal type 1 0.536 0.621 0.33
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.410 1 0 2003 2010
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.367 0.793 0.97
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.400 1.000 8 0 2003 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.380 1.000 5 0 2003 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.370 1.000 6 0 2003 2016
Entrez Id: 6752
Gene Symbol: SSTR2
SSTR2
somatostatin receptor 2 0.551 0.517 0.43
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.360 1.000 5 0 2003 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.339 0.862 7.0E-18
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.360 1.000 5 0 2001 2013
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.393 0.828 1.00
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.360 1.000 3 0 2004 2015
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
pancreatic and duodenal homeobox 1 0.557 0.483 2.0E-02
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.360 1.000 2 0 1999 2016
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.342 0.862
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.350 1.000 4 0 2003 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.350 0.667 3 0 1999 2013
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
plasminogen activator, urokinase 0.434 0.690 2.1E-06
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.350 1.000 2 0 1999 2009
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.432 0.759 0.11
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.340 4 0 2002 2008
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.388 0.828 0.14
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.340 1.000 3 0 2000 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.336 0.931 0.17
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.340 1.000 3 0 2002 2014
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
mesothelin 0.565 0.483 8.2E-23
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.340 1.000 2 0 2002 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.340 1.000 2 0 1991 2009
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
neuropilin 1 0.521 0.690 1.00
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.330 3 0 2004 2008
Entrez Id: 1647
Gene Symbol: GADD45A
GADD45A
growth arrest and DNA damage inducible alpha 0.546 0.690 4.3E-02
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.330 3 0 2002 2009
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm
disease 0.330 1.000 2 0 2002 2014