Source: GENOMICS_ENGLAND

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
ETS variant 6 0.509 0.655 0.99
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.700 strong 1.000 2 0 1995 2017
Entrez Id: 867
Gene Symbol: CBL
CBL
Cbl proto-oncogene 0.550 0.586 4.5E-03
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.610 strong 1.000 1 0 2012 2017
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
SH2B adaptor protein 3 0.575 0.552 6.7E-05
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.500 moderate 2 0 2013 2017
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.440 strong 1.000 2 0 1997 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.437 0.690 0.91
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.430 strong 1.000 2 0 2002 2017
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
PMS1 homolog 2, mismatch repair system component 0.526 0.586 1.2E-27
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 2 0 2017 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
mutS homolog 6 0.495 0.586 2.2E-05
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 2 0 2017 2017
Entrez Id: 2189
Gene Symbol: FANCG
FANCG
FA complementation group G 0.648 0.483 2.1E-13
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 2 0 2017 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 0.926 2 0 1993 2017
Entrez Id: 2178
Gene Symbol: FANCE
FANCE
FA complementation group E 0.636 0.586 8.8E-06
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 2 0 2017 2017
Entrez Id: 2177
Gene Symbol: FANCD2
FANCD2
FA complementation group D2 0.534 0.724 2.1E-30
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 2 0 2017 2017
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
runt related transcription factor 1 0.467 0.690 0.88
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 1.000 2 0 1998 2017
Entrez Id: 2175
Gene Symbol: FANCA
FANCA
FA complementation group A 0.567 0.621 4.3E-68
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 1 0 2017 2017
Entrez Id: 641
Gene Symbol: BLM
BLM
Bloom syndrome RecQ like helicase 0.562 0.690 9.3E-15
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 1 0 2017 2017
Entrez Id: 10456
Gene Symbol: HAX1
HAX1
HCLS1 associated protein X-1 0.667 0.345 8.9E-08
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 1 0 2017 2017
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
FA complementation group C 0.569 0.655 2.6E-13
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.400 strong 1 0 2017 2017
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
protein tyrosine phosphatase, non-receptor type 11 0.429 0.828 1.00
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.380 strong 1.000 1 0 2004 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.340 strong 1.000 0 0 2012 2016
Entrez Id: 2624
Gene Symbol: GATA2
GATA2
GATA binding protein 2 0.536 0.621 0.98
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.330 strong 0.667 2 0 2009 2017
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA
CCAAT enhancer binding protein alpha 0.533 0.586 0.56
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.320 strong 1.000 2 0 2005 2017
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.393 0.862 0.84
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.320 strong 0.500 0 0 2002 2007
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2, DNA repair associated 0.426 0.793 5.5E-24
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.310 strong 2 0 2006 2017
Entrez Id: 51428
Gene Symbol: DDX41
DDX41
DEAD-box helicase 41 0.815 0.276 7.3E-08
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.310 strong 1.000 2 0 2016 2017
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.393 0.828 1.00
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.310 strong < 0.001 2 0 2016 2017
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
regulator of telomere elongation helicase 1 0.509 0.621 1.6E-08
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms
group 0.310 strong 1.000 1 0 2007 2017