Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1, DNA repair associated 0.410 0.862 1.8E-28
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.700 0.988 72 0 1994 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2, DNA repair associated 0.426 0.793 5.5E-24
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.700 1.000 51 0 1996 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.700 0.936 10 0 1990 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.700 1.000 1 0 1991 2013
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.670 1.000 3 0 2001 2013
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.660 0.800 1 0 1998 2011
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.640 1.000 1 0 2005 2016
Entrez Id: 4978
Gene Symbol: OPCML
OPCML
opioid binding protein/cell adhesion molecule like 0.663 0.517 0.25
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.630 < 0.001 2 0 2003 2007
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.590 0.833 4 0 1997 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.500 0.943 14 0 1992 2016
Entrez Id: 580
Gene Symbol: BARD1
BARD1
BRCA1 associated RING domain 1 0.624 0.379 2.2E-24
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.440 1.000 3 0 1998 2006
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
checkpoint kinase 2 0.494 0.621 1.2E-23
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.440 0.667 1 0 2002 2007
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
PMS1 homolog 2, mismatch repair system component 0.526 0.586 1.2E-27
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.410 1 0 2006 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.400 1.000 12 0 1996 2016
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
mucin 16, cell surface associated 0.580 0.517 1.1E-109
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.400 0.882 5 0 1988 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.400 0.909 3 0 2002 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.390 1.000 4 0 2004 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.360 1.000 2 0 1999 2013
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.360 1.000 1 0 1998 2014
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.387 0.862 1.00
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.340 1.000 3 0 2005 2012
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
marker of proliferation Ki-67 0.475 0.655 1.0E-27
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.340 1.000 2 0 2002 2015
Entrez Id: 208
Gene Symbol: AKT2
AKT2
AKT serine/threonine kinase 2 0.512 0.655 0.61
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.340 1.000 2 0 1992 2009
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.382 0.724 1.00
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.340 1.000 1 0 1987 2010
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
endothelin receptor type A 0.469 0.828 0.99
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.340 1.000 1 0 2005 2015
Entrez Id: 10381
Gene Symbol: TUBB3
TUBB3
tubulin beta 3 class III 0.569 0.655 1.5E-10
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.330 3 0 2005 2008