Source: ORPHANET

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL 		ribonuclease L 0.579 0.692 2.0E-10
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.700 None 0.958 1 0 2002 2017
Entrez Id: 60528
Gene Symbol: ELAC2
ELAC2 		elaC ribonuclease Z 2 0.670 0.346 1.7E-20
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.600 None 1.000 1 0 2001 2016
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13 		homeobox B13 0.573 0.462 3.7E-08
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.600 None 1.000 1 0 2012 2017
Entrez Id: 4481
Gene Symbol: MSR1
MSR1 		macrophage scavenger receptor 1 0.553 0.654 2.2E-20
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.580 None 1.000 2 0 2002 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		checkpoint kinase 2 0.460 0.808 1.2E-24
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.520 None 1.000 1 0 2003 2003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		BRCA2 DNA repair associated 0.379 0.846 2.4E-25
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.380 None 1.000 1 0 1998 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		BRCA1 DNA repair associated 0.367 0.923 9.2E-29
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.360 None 1.000 2 0 1999 2017
Entrez Id: 4477
Gene Symbol: MSMB
MSMB 		microseminoprotein beta 0.498 0.846 1.6E-02
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.320 None 1.000 3 0 2008 2017
Entrez Id: 4683
Gene Symbol: NBN
NBN 		nibrin 0.467 0.808 2.2E-16
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.310 None 1.000 2 0 2004 2012
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		EPH receptor B2 0.374 0.846 1.00
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.310 None 1.000 1 0 2006 2011
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2 		steroid 5 alpha-reductase 2 0.564 0.615
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.310 None < 0.001 0 0 2003 2003
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B 		HNF1 homeobox B 0.473 0.808 1.00
CUI: C2931456
Disease: Prostate cancer, familial
Prostate cancer, familial 		disease 0.300 None 1.000 1 0 2008 2008