Source: PSYGENET

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
5-hydroxytryptamine receptor 2A 0.488 0.759 0.48
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.800 0.600 5 0 1997 2015
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
tryptophan hydroxylase 2 0.562 0.552 3.3E-06
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
disease 0.800 0.800 5 0 2005 2018
Entrez Id: 6285
Gene Symbol: S100B
S100B
S100 calcium binding protein B 0.443 0.862 4.7E-02
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.710 1.000 4 0 2005 2012
Entrez Id: 4852
Gene Symbol: NPY
NPY
neuropeptide Y 0.469 0.690 0.16
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
disease 0.710 1.000 2 0 2003 2010
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide 0.525 0.759 1.1E-06
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
disease 0.700 1.000 5 0 1994 2018
Entrez Id: 126
Gene Symbol: ADH1C
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide 0.567 0.655
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
disease 0.700 1.000 5 0 1991 2018
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
aldehyde dehydrogenase 2 family member 0.481 0.862 2.5E-09
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
disease 0.700 1.000 5 0 1991 2018
Entrez Id: 288
Gene Symbol: ANK3
ANK3
ankyrin 3 0.602 0.379 1.00
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.700 1.000 5 0 2009 2018
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
calcium voltage-gated channel subunit alpha1 C 0.575 0.517 1.00
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.700 0.800 5 0 2009 2018
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2 0.624 0.586 1.00
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.640 1.000 3 0 2008 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.600 1.000 5 0 2002 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0011570
Disease: Mental Depression
Mental Depression
disease 0.600 1.000 5 0 2003 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 5 0 2003 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
disease 0.600 1.000 5 0 2005 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT
catechol-O-methyltransferase 0.426 0.897 1.3E-05
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.600 1.000 5 0 1997 2018
Entrez Id: 1392
Gene Symbol: CRH
CRH
corticotropin releasing hormone 0.456 0.759 0.72
CUI: C0011570
Disease: Mental Depression
Mental Depression
disease 0.600 1.000 5 0 1992 2018
Entrez Id: 1392
Gene Symbol: CRH
CRH
corticotropin releasing hormone 0.456 0.759 0.72
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 5 0 1992 2018
Entrez Id: 1392
Gene Symbol: CRH
CRH
corticotropin releasing hormone 0.456 0.759 0.72
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
disease 0.600 1.000 5 0 1992 2016
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
corticotropin releasing hormone receptor 1 0.545 0.690 3.0E-05
CUI: C0011570
Disease: Mental Depression
Mental Depression
disease 0.600 1.000 5 0 2004 2016
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
corticotropin releasing hormone receptor 1 0.545 0.690 3.0E-05
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
disease 0.600 1.000 5 0 2006 2016
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.473 0.759 3.9E-07
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
disease 0.600 1.000 5 0 1995 2015
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
dopamine receptor D1 0.555 0.517 0.94
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
disease 0.600 1.000 5 0 1992 2015
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
dopamine receptor D2 0.454 0.724 0.79
CUI: C0011570
Disease: Mental Depression
Mental Depression
disease 0.600 1.000 5 0 2002 2015
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
dopamine receptor D2 0.454 0.724 0.79
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
disease 0.600 1.000 5 0 1994 2014
Entrez Id: 2289
Gene Symbol: FKBP5
FKBP5
FK506 binding protein 5 0.572 0.655 0.68
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
disease 0.600 0.800 5 0 2009 2018