Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 Biomarker LHGDN A role for CA9 as an endogenous marker of tumor hypoxia is currently not supported by available clinical data. 18290322

2008

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 Biomarker LHGDN CA9 might be a marker of clinically important hypoxia. 11705854

2001

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 Biomarker LHGDN Cell hypoxia activates the capacity of tumor-associated CA9 to acidify extracellular pH. 15556624

2005

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN Expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and carbonic anhydrase IX (CA IX) are markers of cellular hypoxia. 17674038

2007

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. 12615703

2003

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN findings show that CA9 is correlated with poor prognosis and malignant phenotype in patients with oesophageal squamous cell carcinoma, and was upregulated by hypoxia 18841153

2008

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN mCA IX is a marker of tumor cell hypoxia, and absence of CA IX staining close to microvessels suggests that these vessels are functionally active; pCA IX expression is representative of an aggressive phenotype 12560438

2003

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN Coexpression of HIF-1alpha and CAIX in the epithelium in phyllodes tumors points to epithelial hypoxia, most probably caused by relatively distant blood vessels. 16168127

2005

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN MAPK cascade is involved in the regulation of CA9 gene expression under both hypoxia and high cell density. 15833446

2005

Entrez Id: 768
Gene Symbol: CA9
CA9
CUI: C0003130
Disease: Anoxia
Anoxia
0.400 AlteredExpression LHGDN Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase. 12154057

2002