×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Kidney Failure, Chronic
0.600
Biomarker
RGD
Only animals from the 1WIK group developed severe chronic renal failure , glomerulosclerosis, interstitial fibrosis, and upregulation of transforming growth factor-beta(1 ) (TGF-beta(1 )) gene, which was associated with increased TGF-beta(1 ) protein expression in tubular epithelial cells, arterioles, and in areas of mononuclear interstitial cell infiltrate.
10919844 2000
×
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Kidney Failure, Chronic
0.600
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
Kidney Failure, Chronic
0.600
Biomarker
RGD
Our findings indicate localized expression of MCP-1 in proximal tubular cells in the remnant kidney and suggest that MCP-1 in proximal tubular cells is involved in tubulointerstitial damage in chronic kidney failure associated with glomerular hypertension.
12080327 2002
×
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
Kidney Failure, Chronic
0.570
Biomarker
RGD
Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.
20631677 2010
×
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
Kidney Failure, Chronic
0.550
Biomarker
RGD
Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.
19420110 2009
×
Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1
Kidney Failure, Chronic
0.530
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144 2014
×
Entrez Id: 5970
Gene Symbol: RELA
RELA
Kidney Failure, Chronic
0.510
Biomarker
RGD
Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction.
18077597 2008
×
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
Kidney Failure, Chronic
0.510
Biomarker
RGD
Renal tissue abundance of gp91(phox ) subunit of NAD(P)H oxidase was elevated in the untreated CRF group and was partially reduced in the iron dextran-treated CRF group.
15550752 2005
×
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
Kidney Failure, Chronic
0.500
Biomarker
RGD
Niacin improves renal lipid metabolism and slows progression in chronic kidney disease.
19878707 2010
×
Entrez Id: 847
Gene Symbol: CAT
CAT
Kidney Failure, Chronic
0.500
Biomarker
RGD
Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure.
20007347 2010
×
Entrez Id: 873
Gene Symbol: CBR1
CBR1
Kidney Failure, Chronic
0.500
Biomarker
RGD
Effect of experimental kidney disease on the functional expression of hepatic reductases.
25332430 2015
×
Entrez Id: 6721
Gene Symbol: SREBF2
SREBF2
Kidney Failure, Chronic
0.500
Biomarker
RGD
Despite increased SREBP-2 gene expression we found LDL-receptor mRNA level to be lower than in controls, suggesting SREBP-2 independent mechanisms of LDL-receptor transcriptional regulation in CRF rats.
16814791 2007
×
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
Kidney Failure, Chronic
0.500
Biomarker
RGD
Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin.
21119529 2011
×
Entrez Id: 4036
Gene Symbol: LRP2
LRP2
Kidney Failure, Chronic
0.310
Biomarker
RGD
Modulation of gene expression by moxonidine in rats with chronic renal failure.
15266031 2004
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Kidney Failure, Chronic
0.300
Biomarker
RGD
Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats.
23548814 2013
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Kidney Failure, Chronic
0.300
Biomarker
RGD
The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.
21826734 2011
×
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
Kidney Failure, Chronic
0.300
Biomarker
RGD
Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury.
12089373 2002
×
Entrez Id: 5741
Gene Symbol: PTH
PTH
Kidney Failure, Chronic
0.300
Biomarker
RGD
Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats.
22517117 2012
×
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
Kidney Failure, Chronic
0.300
Biomarker
RGD
Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy.
12110012 2002
×
Entrez Id: 8074
Gene Symbol: FGF23
FGF23
Kidney Failure, Chronic
0.300
Biomarker
RGD
Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease.
20016468 2010
×
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
Kidney Failure, Chronic
0.300
Biomarker
RGD
Protein and mRNA expression levels of Oat1, Oat 3, Oct1, and Oct2 were significantly decreased in adenine-induced CRF rats.
23280877 2013
×
Entrez Id: 6569
Gene Symbol: SLC34A1
SLC34A1
Kidney Failure, Chronic
0.300
Biomarker
RGD
The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.
21826734 2011
×
Entrez Id: 6569
Gene Symbol: SLC34A1
SLC34A1
Kidney Failure, Chronic
0.300
Biomarker
RGD
Regulation of NaPi-IIa mRNA and transporter protein in chronic renal failure: role of parathyroid hormone (PTH) and dietary phosphate (Pi).
15452708 2004
×
Entrez Id: 9365
Gene Symbol: KL
KL
Kidney Failure, Chronic
0.300
Biomarker
RGD
This is the first report showing the expression of the klotho gene in the kidney is regulated under sustained circulatory stress such as long-term hypertension, diabetes mellitus, and chronic renal failure .
9731228 1998
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Kidney Failure, Chronic
0.300
Biomarker
RGD
Urine levels of NOx and the expression of glomerular eNOS and tubulointerstitial nNOS were significantly decreased in CRF rats compared with normal rats.
18089446 2008