×
Entrez Id:
5243
Gene Symbol:
ABCB1
ABCB1
Kidney Failure, Chronic
0.210
Biomarker
RGD
Protein expression of Pgp , MRP2, and MRP3 were reduced by more than 40% (p < 0.01) in CRF rats, whereas Oatp2 and Oatp3 expression remained unchanged.
17135344
2007
×
Entrez Id:
1244
Gene Symbol:
ABCC2
ABCC2
Kidney Failure, Chronic
0.200
Biomarker
RGD
Pgp and MRP2 activities were decreased by 30 and 25%, respectively, in CRF rats compared with control (p < 0.05).
17135344
2007
×
Entrez Id:
8714
Gene Symbol:
ABCC3
ABCC3
Kidney Failure, Chronic
0.200
Biomarker
RGD
Protein expression of Pgp, MRP2, and MRP3 were reduced by more than 40% (p < 0.01) in CRF rats, whereas Oatp2 and Oatp3 expression remained unchanged.
17135344
2007
×
Entrez Id:
38
Gene Symbol:
ACAT1
ACAT1
Kidney Failure, Chronic
0.500
Biomarker
RGD
Niacin improves renal lipid metabolism and slows progression in chronic kidney disease.
19878707
2010
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Kidney Failure, Chronic
0.600
Therapeutic
RGD
Although compelling evidence of a beneficial effect exists for the use of angiotensin-converting enzyme inhibitors (ACEIs) and low-protein diets, there is little evidence on whether carbon adsorbent has an effect on retardation of the progression of CRF .
14586729
2003
×
Entrez Id:
9370
Gene Symbol:
ADIPOQ
ADIPOQ
Kidney Failure, Chronic
0.600
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144
2014
×
Entrez Id:
51094
Gene Symbol:
ADIPOR1
ADIPOR1
Kidney Failure, Chronic
0.530
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144
2014
×
Entrez Id:
79602
Gene Symbol:
ADIPOR2
ADIPOR2
Kidney Failure, Chronic
0.210
Biomarker
RGD
Changes of adiponectin and its receptors in rats following chronic renal failure.
24028144
2014
×
Entrez Id:
185
Gene Symbol:
AGTR1
AGTR1
Kidney Failure, Chronic
0.300
Biomarker
RGD
Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury.
12089373
2002
×
Entrez Id:
186
Gene Symbol:
AGTR2
AGTR2
Kidney Failure, Chronic
0.200
Biomarker
RGD
Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury.
12089373
2002
×
Entrez Id:
384
Gene Symbol:
ARG2
ARG2
Kidney Failure, Chronic
0.200
Biomarker
RGD
Effect of chronic renal failure on arginase and argininosuccinate synthetase expression.
16809898
2006
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Kidney Failure, Chronic
0.220
Therapeutic
RGD
Epoetin delta as an antifibrotic agent in the remnant kidney rat: a possible role for transforming growth factor beta and hepatocyte growth factor.
20424483
2010
×
Entrez Id:
8678
Gene Symbol:
BECN1
BECN1
Kidney Failure, Chronic
0.200
Biomarker
RGD
Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach.
24090408
2013
×
Entrez Id:
632
Gene Symbol:
BGLAP
BGLAP
Kidney Failure, Chronic
0.210
Biomarker
RGD
Serum osteocalcin and to a lesser extend tartrate-resistant acid phosphatase and urinary pyridinoline and deoxypyridinoline crosslinks were higher in the CRF animals compared to the shams, particularly in the animals of the HPD group with more pronounced CRF .
17365904
2007
×
Entrez Id:
664
Gene Symbol:
BNIP3
BNIP3
Kidney Failure, Chronic
0.200
Biomarker
RGD
Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach.
24090408
2013
×
Entrez Id:
729
Gene Symbol:
C6
C6
Kidney Failure, Chronic
0.200
ModifyingMutation
RGD
C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys.
11912252
2002
×
Entrez Id:
847
Gene Symbol:
CAT
CAT
Kidney Failure, Chronic
0.500
Biomarker
RGD
Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure.
20007347
2010
×
Entrez Id:
873
Gene Symbol:
CBR1
CBR1
Kidney Failure, Chronic
0.500
Biomarker
RGD
Effect of experimental kidney disease on the functional expression of hepatic reductases.
25332430
2015
×
Entrez Id:
6347
Gene Symbol:
CCL2
CCL2
Kidney Failure, Chronic
0.600
Biomarker
RGD
Our findings indicate localized expression of MCP-1 in proximal tubular cells in the remnant kidney and suggest that MCP-1 in proximal tubular cells is involved in tubulointerstitial damage in chronic kidney failure associated with glomerular hypertension.
12080327
2002
×
Entrez Id:
6347
Gene Symbol:
CCL2
CCL2
Kidney Failure, Chronic
0.600
Therapeutic
RGD
Sedentary CRF rats exhibited azotemia, hypertension, anemia, oxidative stress, activation of NF-kappaB and upregulations of reactive oxygen species-generating enzyme, NAD(P)H oxidase, MCP-1 , cyclooxygenase-2 (COX-2), and PAI-1 in LV.
18797164
2009
×
Entrez Id:
6352
Gene Symbol:
CCL5
CCL5
Kidney Failure, Chronic
0.220
Biomarker
RGD
Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
19535570
2009
×
Entrez Id:
1234
Gene Symbol:
CCR5
CCR5
Kidney Failure, Chronic
0.260
Biomarker
RGD
Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
19535570
2009
×
Entrez Id:
1191
Gene Symbol:
CLU
CLU
Kidney Failure, Chronic
0.210
Biomarker
RGD
Urinary biomarkers track the progression of nephropathy in hypertensive and obese rats.
24325231
2014
×
Entrez Id:
1535
Gene Symbol:
CYBA
CYBA
Kidney Failure, Chronic
0.550
Biomarker
RGD
Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.
19420110
2009
×
Entrez Id:
1536
Gene Symbol:
CYBB
CYBB
Kidney Failure, Chronic
0.510
Biomarker
RGD
Renal tissue abundance of gp91(phox ) subunit of NAD(P)H oxidase was elevated in the untreated CRF group and was partially reduced in the iron dextran-treated CRF group.
15550752
2005