Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
MYCN proto-oncogene, bHLH transcription factor 0.454 0.808 0.89
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.700 None 0.971 932 3 1984 2020
Entrez Id: 238
Gene Symbol: ALK
ALK
ALK receptor tyrosine kinase 0.396 0.846 3.2E-06
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.700 None 0.957 180 5 2000 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.400 None 0.955 176 8 1988 2019
Entrez Id: 351
Gene Symbol: APP
APP
amyloid beta precursor protein 0.422 0.846 4.7E-02
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.990 100 5 1989 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.972 72 0 1991 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.986 71 0 1993 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.600 None 0.984 62 0 1985 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
synuclein alpha 0.427 0.885 0.88
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.967 60 3 1998 2020
Entrez Id: 7054
Gene Symbol: TH
TH
tyrosine hydroxylase 0.462 0.885 1.7E-06
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.400 None 0.950 59 2 1989 2018
Entrez Id: 8929
Gene Symbol: PHOX2B
PHOX2B
paired like homeobox 2B 0.565 0.731 0.94
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.800 None 0.897 56 2 2004 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.981 54 0 2000 2019
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 1.000 50 0 1989 2019
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1
neurotrophic receptor tyrosine kinase 1 0.422 0.808 2.0E-06
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.400 None 1.000 48 1 1992 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.200 None 0.953 43 0 2002 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.951 41 0 2002 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.404 0.923 3.7E-06
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.951 41 1 2000 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.362 0.846 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.925 40 0 1995 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.950 40 0 2002 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.950 40 0 2002 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 0.974 39 1 2000 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 1.000 38 0 1997 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.200 None 1.000 37 0 1990 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 1.000 36 1 1990 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.400 None 0.943 34 0 1989 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.379 0.962 0.18
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.100 None 1.000 34 4 1988 2019