Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 None 0.946 3042 25 1991 2020
Entrez Id: 351
Gene Symbol: APP
APP
amyloid beta precursor protein 0.422 0.846 4.7E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.900 None 0.981 2575 61 1987 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
microtubule associated protein tau 0.446 0.923 6.0E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 None 0.990 997 23 1988 2020
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
presenilin 1 0.469 0.846 0.97
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 None 0.971 682 62 1990 2020
Entrez Id: 23621
Gene Symbol: BACE1
BACE1
beta-secretase 1 0.559 0.769 0.88
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 None 0.985 472 4 1999 2020
Entrez Id: 43
Gene Symbol: ACHE
ACHE
acetylcholinesterase (Cartwright blood group) 0.445 0.885 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.985 388 1 1991 2020
Entrez Id: 590
Gene Symbol: BCHE
BCHE
butyrylcholinesterase 0.447 0.923 1.1E-13
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.962 343 3 1995 2020
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
colony stimulating factor 2 0.330 0.962 0.83
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.100 None 0.966 294 0 2004 2020
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
laminin subunit gamma 2 0.389 0.923 2.9E-12
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.100 None 0.965 289 0 2010 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 None 0.958 239 10 1991 2020
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
triggering receptor expressed on myeloid cells 2 0.519 0.769 3.3E-09
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 limited 0.977 214 13 2007 2020
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2
presenilin 2 0.550 0.654 5.4E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 None 0.977 177 12 1995 2020
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2
succinate-CoA ligase ADP-forming subunit beta 0.566 0.654 2.3E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.100 None 0.982 167 0 1993 2020
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
synuclein alpha 0.427 0.885 0.88
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.100 None 0.962 159 5 1993 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.963 134 2 1998 2020
Entrez Id: 1191
Gene Symbol: CLU
CLU
clusterin 0.426 0.885 7.8E-05
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 None 0.940 133 8 1991 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 None 0.966 116 0 1989 2020
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
glycogen synthase kinase 3 beta 0.430 0.846 0.96
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 None 0.982 113 4 2000 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.938 112 1 1993 2019
Entrez Id: 6653
Gene Symbol: SORL1
SORL1
sortilin related receptor 1 0.582 0.692 7.7E-11
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 None 0.973 111 18 2004 2020
Entrez Id: 345643
Gene Symbol: MCIDAS
MCIDAS
multiciliate differentiation and DNA synthesis associated cell cycle protein 0.566 0.769 1.3E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.100 None 0.945 110 0 2002 2020
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
prion protein 0.445 0.923 6.3E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.902 102 3 1986 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.300 None 0.969 97 1 1989 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.900 strong 0.915 94 8 1998 2020
Entrez Id: 10452
Gene Symbol: TOMM40
TOMM40
translocase of outer mitochondrial membrane 40 0.590 0.538 0.99
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 None 0.978 92 29 2009 2020