Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.500 None 0.985 1299 31 1988 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.500 None 0.942 555 33 1989 2020
Entrez Id: 238
Gene Symbol: ALK
ALK
ALK receptor tyrosine kinase 0.396 0.846 3.2E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.982 283 2 2008 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.700 None 0.980 254 4 1985 2020
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.917 180 1 1992 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.977 175 0 2015 2020
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
cytochrome P450 family 1 subfamily A member 1 0.436 0.846 1.1E-17
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.905 168 3 1977 2019
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 1.000 111 3 2000 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.963 109 4 1994 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.400 None 0.972 107 5 1989 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.500 None 0.972 105 2 2002 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 1.000 102 1 2006 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.970 101 3 1996 2020
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
glutathione S-transferase theta 1 0.393 0.923 1.5E-04
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.874 87 0 1997 2018
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
X-ray repair cross complementing 1 0.421 0.923 6.3E-09
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.931 87 12 2001 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.964 83 1 2003 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.940 83 5 1995 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.976 82 0 2003 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.963 82 1 2003 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.988 80 1 2007 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.912 80 4 1991 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.973 75 2 1991 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.357 0.923 8.5E-17
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.986 73 1 1987 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 0.971 70 4 2000 2019
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS
hematopoietic prostaglandin D synthase 0.388 0.923 1.8E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.100 None 1.000 69 0 1991 2018