Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
solute carrier family 6 member 4 0.446 0.724 0.26
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 9 0 1997 2018
Entrez Id: 4852
Gene Symbol: NPY
NPY
neuropeptide Y 0.469 0.690 0.16
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 7 0 1998 2015
Entrez Id: 1392
Gene Symbol: CRH
CRH
corticotropin releasing hormone 0.456 0.759 0.72
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 7 0 1992 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 7 0 2003 2018
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
potassium two pore domain channel subfamily K member 2 0.667 0.276 2.1E-02
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.560 1.000 6 0 2007 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 0.600 6 0 1995 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.560 1.000 6 0 2003 2014
Entrez Id: 5443
Gene Symbol: POMC
POMC
proopiomelanocortin 0.382 0.862 9.4E-05
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.530 1.000 6 0 2003 2015
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
nuclear receptor subfamily 3 group C member 1 0.427 0.793 0.98
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 0.800 6 0 1999 2018
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
tryptophan hydroxylase 2 0.562 0.552 3.3E-06
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 6 0 2005 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.354 0.828 1.2E-09
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.600 1.000 6 0 1997 2017
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
5-hydroxytryptamine receptor 7 0.607 0.379 4.8E-02
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.520 1.000 6 0 2004 2013
Entrez Id: 2562
Gene Symbol: GABRB3
GABRB3
gamma-aminobutyric acid type A receptor beta3 subunit 0.572 0.517 0.96
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.330 1.000 5 0 2002 2013
Entrez Id: 6285
Gene Symbol: S100B
S100B
S100 calcium binding protein B 0.443 0.862 4.7E-02
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.340 1.000 5 0 1996 2011
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.423 0.759 2.1E-07
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.340 1.000 5 0 2005 2013
Entrez Id: 2784
Gene Symbol: GNB3
GNB3
G protein subunit beta 3 0.533 0.724 2.9E-11
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.350 1.000 5 0 2002 2015
Entrez Id: 2847
Gene Symbol: MCHR1
MCHR1
melanin concentrating hormone receptor 1 0.690 0.310 3.5E-05
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.320 1.000 5 0 2005 2013
Entrez Id: 2890
Gene Symbol: GRIA1
GRIA1
glutamate ionotropic receptor AMPA type subunit 1 0.636 0.414 1.00
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.320 0.600 5 0 2013 2015
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B 0.561 0.483 1.00
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.310 0.800 5 0 2010 2015
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.400 1.000 5 0 2002 2016
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
solute carrier family 6 member 2 0.534 0.724 6.5E-02
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.400 0.800 5 0 2008 2018
Entrez Id: 7054
Gene Symbol: TH
TH
tyrosine hydroxylase 0.498 0.759 2.5E-06
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.310 0.800 5 0 2000 2014
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
dopamine receptor D2 0.454 0.724 0.79
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.500 1.000 5 0 2002 2015
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
dopamine receptor D3 0.527 0.552 2.0E-03
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.320 1.000 5 0 2007 2013
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
dopamine receptor D4 0.536 0.414 7.1E-09
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease 0.400 1.000 5 0 1998 2018