Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0003130
Disease: Anoxia
Anoxia
0.030 AlteredExpression LHGDN Our studies show that PlGF-induced expression of the potent vasoconstrictor ET-1 and its cognate ET-BR receptor occur via activation of HIF-1 alpha, independent of hypoxia. 18411415

2008

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0003130
Disease: Anoxia
Anoxia
0.030 GeneticVariation LHGDN Endothelin-1 gene variants and levels associate with adaptation to hypobaric hypoxia in high-altitude natives. 16466695

2006

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0003130
Disease: Anoxia
Anoxia
0.030 AlteredExpression LHGDN After exposure to hypoxia equal to post-transplant environment oxygen tension, mRNA levels of ET-1 and ETB-receptor of human islets were robustly induced whereas ETA-receptor mRNA did not show significant changes. 18326921

2008