DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Rheumatoid Arthritis ×

Gene: AGER ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	177
Gene Symbol:	AGER

AGER

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.470

AlteredExpression

LHGDN

RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro.

18078623

2008

Entrez Id:	177
Gene Symbol:	AGER

AGER

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.470

GeneticVariation

LHGDN

RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response.

12070776

2002

Entrez Id:	177
Gene Symbol:	AGER

AGER

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.470

Biomarker

LHGDN

Serum amyloid A activates nuclear factor-kappaB in rheumatoid synovial fibroblasts through binding to receptor of advanced glycation end-products.

18322992

2008